Critical Assessment of In Vitro Screening of α-Glucosidase Inhibitors from Plants with Acarbose as a Reference Standard.
Sign Up to like & getrecommendations! Published in 2021 at "Planta medica"
DOI: 10.1055/a-1557-7379
Abstract: Postprandial hyperglycemia is treated with the oral antidiabetic drug acarbose, an intestinal α-glucosidase inhibitor. Side effects of acarbose motivated a growing number of screening studies to identify novel α-glucosidase inhibitors derived from plant extracts and… read more here.
Keywords: screening studies; glucosidase inhibitors; assessment; reference standard ... See more keywords
FluoroGold‐labeled organotypic retinal explant culture (FLOREC) for neurodegeneration and neurotoxicity screening studies
Sign Up to like & getrecommendations! Published in 2017 at "Acta Ophthalmologica"
DOI: 10.1111/j.1755-3768.2017.0f076
Abstract: Purpose To create a fast and reproducible system for retinal drugs toxicity screening. Methods In this study, we used retinal explants culture from 4 weeks old Wistar rats (n = 16). First, to determine the effect of FluoroGold… read more here.
Keywords: screening studies; medium; culture medium; neurotoxicity ... See more keywords
Large‐scale screening studies for atrial fibrillation – is it worth the effort?
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DOI: 10.1111/joim.13217
Abstract: Atrial fibrillation (AF) is a common disease with increasing prevalence, approximately 3.2% in the adult population. In addition, about one third of AF cases are considered asymptomatic. Due to increased longevity, increased detection and increased… read more here.
Keywords: atrial fibrillation; screening studies; large scale; scale screening ... See more keywords