A High-Content Screening Technology for Quantitatively Studying Podocyte Dynamics.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in chronic kidney disease"
DOI: 10.1053/j.ackd.2017.04.001
Abstract: Podocytes form the visceral layer of a kidney glomerulus and express a characteristic octopus-like cellular architecture specialized for the ultrafiltration of blood. The cytoskeletal dynamics and structural elasticity of podocytes rely on the self-organization of… read more here.
Keywords: screening technology; high content; podocyte; content screening ... See more keywords
Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.00016
Abstract: Parkinson’s disease (PD) is the second most common neurodegenerative disorder characterized by the accumulation of protein aggregates (namely Lewy bodies) in dopaminergic neurons in the substantia nigra region of the brain. Alpha-synuclein (α-syn) is the… read more here.
Keywords: genome wide; crispr cas9; screening technology; canthin one ... See more keywords