A drug screening toolkit based on the –1 ribosomal frameshifting of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e04793
Abstract: The –1 ribosomal frameshifting is vital for the translation of the open reading frame (ORF)1b in SARS-CoV-2. The products of ORF1b participate in viral replication. Therefore, changing the frameshift frequency reduces the survival of the… read more here.
Keywords: frameshifting sars; ribosomal frameshifting; screening toolkit; drug screening ... See more keywords