Flavonoids as BACE1 inhibitors: QSAR modelling, screening and in vitro evaluation.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.09.232
Abstract: Alzheimer's disease (AD) is marked by the presence of amyloid plaques, neurofibrillary tangles, oxidatively damaged neuronal macromolecules and redox sensitive ions. Reduction of amyloid plaques and oxidative stress emerge as a convincing treatment strategy. Plaque… read more here.
Keywords: bace1 inhibitors; modelling screening; flavonoids bace1; inhibitors qsar ... See more keywords
Involvement of Anthocyanin Biosynthesis of Cabernet Sauvignon Grape Skins in Response to Field Screening and In Vitro Culture Irradiating Infrared Radiation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c03838
Abstract: To study the role of infrared (IR) radiation in the color change of the grape berry, field screening (IR-) and in vitro culture irradiation (IR+) were used. Acylated anthocyanin biosyntheses, including the biosynthesis of malvidin… read more here.
Keywords: grape; biosynthesis; screening vitro; field screening ... See more keywords
In silico screening and in vitro validation of phytocompounds as multidrug efflux pump inhibitor against E. coli
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2022.2029564
Abstract: Abstract Multiple drug resistance (MDR) in bacteria has increased globally in recent times. This has reduced the efficacy of antibiotics and increasing the rate of therapeutic failure. Targeting efflux pump by natural and synthetic compounds… read more here.
Keywords: silico screening; screening vitro; chlorogenic acid; efflux pump ... See more keywords
Virtual Screening and in Vitro Evaluation to Identify a Potential Xanthine Oxidase Inhibitor Isolated from Vietnamese Uvaria cordata
Sign Up to like & getrecommendations! Published in 2022 at "Natural Product Communications"
DOI: 10.1177/1934578x221080339
Abstract: Xanthine oxidase (XO) is a potential target for gout disease experiments on animals and humans. Using a molecular docking technique to search for anti-XO compounds from Vietnamese medicinal plants, we discovered that numerous compounds from… read more here.
Keywords: uvaria cordata; screening vitro; virtual screening; xanthine oxidase ... See more keywords
PHYTOCHEMICAL SCREENING AND IN-VITRO ANTI-FUNGAL ACTIVITY OF “TRIDAX PROCUMBENS L.
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Approximate Reasoning"
DOI: 10.21474/ijar01/4952
Abstract: * Y. Bhagyasri, N. Vinay reddy, M. Dattatrya, K. Divya and * N. Siva Subramanian. Gland Institute Of Pharmaceutical science, Sy No.551, Shangri-La, Kothapet (v), Sivampet (m), Near Narsapur , Medak (dist) Telangana. ...................................................................................................................... Manuscript… read more here.
Keywords: anti fungal; phytochemical screening; vitro anti; screening vitro ... See more keywords
Combining virtual screening and in vitro evaluation for the discovery of potential CYP11B2 inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2022-0119
Abstract: Aim: To search for highly bioactive hits for CYP11B2 inhibitors by virtual screening and in vitro evaluation. Materials & methods: Virtual screening of potential CYP11B2 inhibitors was performed by molecular docking and molecular dynamics simulation.… read more here.
Keywords: screening vitro; cyp11b2 inhibitors; virtual screening; potential cyp11b2 ... See more keywords