Chemical screening in zebrafish for novel biological and therapeutic discovery.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in cell biology"
DOI: 10.1016/bs.mcb.2016.10.004
Abstract: Zebrafish chemical screening allows for an in vivo assessment of small molecule modulation of biological processes. Compound toxicities, chemical alterations by metabolism, pharmacokinetic and pharmacodynamic properties, and modulation of cell niches can be studied with… read more here.
Keywords: therapeutic discovery; chemical screening; screening zebrafish; discovery chemical ... See more keywords
Virtual screening and zebrafish models in tandem, for drug discovery and development.
Sign Up to like & getrecommendations! Published in 2022 at "Expert opinion on drug discovery"
DOI: 10.1080/17460441.2022.2147503
Abstract: INTRODUCTION The combination of Virtual Screening (VS) techniques with in vivo screening in the zebrafish model is currently being used in tandem for drug development in a faster and more efficient way. AREAS COVERED We… read more here.
Keywords: screening zebrafish; drug discovery; virtual screening; drug ... See more keywords
Synergizing Virtual Screening and Zebrafish Models to Identify Resveratrol-Derived Antiaging Polyphenols
Sign Up to like & getrecommendations! Published in 2025 at "Pharmaceuticals"
DOI: 10.3390/ph18111630
Abstract: Background: Telomere shortening and chronic inflammation are well-established hallmarks of aging and age-related diseases, often resulting in impaired cellular function. Identifying compounds with anti-aging potential is therefore crucial to promote healthy aging and extend lifespan.… read more here.
Keywords: virtual screening; identify resveratrol; screening zebrafish; zebrafish models ... See more keywords