Analysis of combinatorial CRISPR screens with the Orthrus scoring pipeline.
Sign Up to like & getrecommendations! Published in 2021 at "Nature protocols"
DOI: 10.1038/s41596-021-00596-0
Abstract: The continued improvement of combinatorial CRISPR screening platforms necessitates the development of new computational pipelines for scoring combinatorial screening data. Unlike for single-guide RNA (sgRNA) pooled screening platforms, combinatorial scoring for multiplexed systems is confounded… read more here.
Keywords: crispr; screens orthrus; combinatorial crispr; screening data ... See more keywords