Scriptaid improves the reprogramming of donor cells and enhances canine-porcine interspecies embryo development.
Sign Up to like & getrecommendations! Published in 2018 at "Reproductive biology"
DOI: 10.1016/j.repbio.2017.11.001
Abstract: Histone methylation, histone acetylation, and DNA methylation are the important factors for somatic cell nuclear transfer (SCNT). Histone deacetylase inhibitors (HDACi) and DNA methyltransferase inhibitors (DNMTi) have been used to improve cloning efficiency. In particular,… read more here.
Keywords: development; cell; scriptaid; canine porcine ... See more keywords
Scriptaid Upregulates Expression of Development-Related Genes, Inhibits Apoptosis, and Improves the Development of Somatic Cell Nuclear Transfer Mini-Pig Embryos.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular reprogramming"
DOI: 10.1089/cell.2016.0033
Abstract: The present study was undertaken to investigate the mechanisms by which Scriptaid treatment improves the developmental competence of somatic cell nuclear transfer (SCNT) mini-pig embryos in vitro. We found that treatment with 500 nmol/L Scriptaid for… read more here.
Keywords: embryos; mini pig; scriptaid; cell ... See more keywords