Identification of de novo mutations in prenatal neurodevelopment-associated genes in schizophrenia in two Han Chinese patient-sibling family-based cohorts
Sign Up to like & getrecommendations! Published in 2020 at "Translational Psychiatry"
DOI: 10.1038/s41398-020-00987-z
Abstract: Schizophrenia (SCZ) is a severe psychiatric disorder with a strong genetic component. High heritability of SCZ suggests a major role for transmitted genetic variants. Furthermore, SCZ is also associated with a marked reduction in fecundity,… read more here.
Keywords: neurodevelopment; scz; novo mutations; mutations prenatal ... See more keywords
Metabolic profiles mediate insomnia-related cognitive impairments in schizophrenia: a large-scale study.
Sign Up to like & getrecommendations! Published in 2025 at "International journal of psychiatry in clinical practice"
DOI: 10.1080/13651501.2025.2581683
Abstract: BACKGROUND Insomnia has a significant impact on metabolic changes and cognitive impairments in schizophrenia (SCZ) patients. This study aimed to explore these relationships in SCZ patients. METHODS A total of 609 SCZ patients were recruited.… read more here.
Keywords: insomnia; scz patients; cognitive impairments; scale ... See more keywords
Alterations in the plasma concentrations of BDNF, proBDNF, and MMP-9 in patients with schizophrenia
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Medical Research"
DOI: 10.1186/s40001-025-03153-7
Abstract: Schizophrenia (SCZ) is a complex psychiatric disorder characterized by altered brain neurotrophic factor signaling. This study aimed to investigate the plasma levels of brain-derived neurotrophic factor (BDNF), its precursor proBDNF, and matrix metalloproteinase-9 (MMP-9) in… read more here.
Keywords: mmp; bdnf probdnf; scz patients; mmp levels ... See more keywords
The Role of Cytokines in Predicting the Efficacy of Acute Stage Treatment in Patients with Schizophrenia
Sign Up to like & getrecommendations! Published in 2020 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s218483
Abstract: Purpose Inflammatory response in schizophrenia (SCz) is related to its underlying pathological mechanism and might be significant in deciding a patient’s prognosis. The current study aims to investigate the differences in the serum inflammation level… read more here.
Keywords: healthy controls; treatment; patients scz; level ... See more keywords
Comparative analysis of the pre- and post-medicative effects of antipsychotic agents on the blood-based oxidative stress biomarkers in patients with schizophrenia: a meta-analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Current neuropharmacology"
DOI: 10.2174/1570159x20666220706101021
Abstract: OBJECTIVES Studies have shown that oxidative stress (OS) is related to the pathophysiology of schizophrenia (SCZ), but whether antipsychotics can induce OS has not been investigated well. Moreover, antipsychotics have differential effects on the OS… read more here.
Keywords: meta analysis; oxidative stress; analysis; scz patients ... See more keywords
Olanzapine-Induced Weight Gain and Glycolipid Metabolism Aberrations in First-Episode and Antipsychotic-Naïve Schizophrenia Patients: A Longitudinal Study
Sign Up to like & getrecommendations! Published in 2024 at "Current Neuropharmacology"
DOI: 10.2174/1570159x23666240918103730
Abstract: Objective Limited research has delved into the comprehensive impact of monotherapy on weight and glycolipid metabolism in schizophrenia (SCZ) patients. Our study aims to longitudinally investigate the multidimensional effects of olanzapine (OLA) monotherapy on weight… read more here.
Keywords: scz; scz patients; ola treatment; glycolipid metabolism ... See more keywords
Peripheral Blood Non-Coding RNA as Biomarker for Schizophrenia: A Review.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin2302042
Abstract: Schizophrenia (SCZ) is a complex and heterogeneous neuropsychiatric disorder that lacks objective diagnostic indicators and the pathogenesis remain unclear. Genetic factors may exert a significant impact on the development of the condition. While obtaining brain… read more here.
Keywords: peripheral blood; schizophrenia; non coding; scz patients ... See more keywords
EEG Microstate Dynamics during Different Physiological Developmental Stages and the Effects of Medication in Schizophrenia.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of integrative neuroscience"
DOI: 10.31083/jin27059
Abstract: BACKGROUND Schizophrenia (SCZ) is associated with abnormal neural activities and brain connectivity. Electroencephalography (EEG) microstate is a voltage topographical representation of temporary brain network activations. Most research on EEG microstates in SCZ has focused on… read more here.
Keywords: microstates class; eeg microstate; scz patients; class ... See more keywords
Establishment of an assistive diagnostic model for schizophrenia with oxidative stress biomarkers
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1158254
Abstract: Objective: In this study, alterations in oxidative stress-related indicators were evaluated in drug-naïve, first-episode schizophrenia (SCZ) patients, and the effectiveness of blood serum glucose, superoxide dismutase (SOD), bilirubin in the objective assistive diagnosis of schizophrenia… read more here.
Keywords: diagnostic model; oxidative stress; assistive diagnostic; scz patients ... See more keywords