Identification of de novo mutations in prenatal neurodevelopment-associated genes in schizophrenia in two Han Chinese patient-sibling family-based cohorts
Sign Up to like & getrecommendations! Published in 2020 at "Translational Psychiatry"
DOI: 10.1038/s41398-020-00987-z
Abstract: Schizophrenia (SCZ) is a severe psychiatric disorder with a strong genetic component. High heritability of SCZ suggests a major role for transmitted genetic variants. Furthermore, SCZ is also associated with a marked reduction in fecundity,… read more here.
Keywords: neurodevelopment; scz; novo mutations; mutations prenatal ... See more keywords
The Role of Cytokines in Predicting the Efficacy of Acute Stage Treatment in Patients with Schizophrenia
Sign Up to like & getrecommendations! Published in 2020 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s218483
Abstract: Purpose Inflammatory response in schizophrenia (SCz) is related to its underlying pathological mechanism and might be significant in deciding a patient’s prognosis. The current study aims to investigate the differences in the serum inflammation level… read more here.
Keywords: healthy controls; treatment; patients scz; level ... See more keywords
Comparative analysis of the pre- and post-medicative effects of antipsychotic agents on the blood-based oxidative stress biomarkers in patients with schizophrenia: a meta-analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Current neuropharmacology"
DOI: 10.2174/1570159x20666220706101021
Abstract: OBJECTIVES Studies have shown that oxidative stress (OS) is related to the pathophysiology of schizophrenia (SCZ), but whether antipsychotics can induce OS has not been investigated well. Moreover, antipsychotics have differential effects on the OS… read more here.
Keywords: meta analysis; oxidative stress; analysis; scz patients ... See more keywords
Establishment of an assistive diagnostic model for schizophrenia with oxidative stress biomarkers
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1158254
Abstract: Objective: In this study, alterations in oxidative stress-related indicators were evaluated in drug-naïve, first-episode schizophrenia (SCZ) patients, and the effectiveness of blood serum glucose, superoxide dismutase (SOD), bilirubin in the objective assistive diagnosis of schizophrenia… read more here.
Keywords: diagnostic model; oxidative stress; assistive diagnostic; scz patients ... See more keywords