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   Articles with "sdc2" as a keyword



Emerging roles of syndecan 2 in epithelial and mesenchymal cancer progression

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recommendations! Published in 2017 at "IUBMB Life"

DOI: 10.1002/iub.1678

Abstract: Syndecan 2 (SDC2) belongs to a four‐member family of evolutionary conserved small type I transmembrane proteoglycans consisting of a protein core to which glycosaminoglycan chains are covalently attached. SDC2 is a cell surface heparan sulfate… read more here.

Keywords: sdc2; emerging roles; cancer progression; roles syndecan ... See more keywords

SDC2 and FN as cargo proteins in circulating extracellular vesicles in obese breast cancer patients with lymph node metastasis

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-17638-2

Abstract: Lymph node metastasis (LNM) is a pivotal determinant of breast cancer (BC) patient prognosis and treatment efficacy. Cell surface heparan sulfate proteoglycans (HSPGs), namely, syndecan-1 (SDC1), SDC2, and SDC4, are involved in cancer progression, metastasis,… read more here.

Keywords: breast cancer; node metastasis; lymph node; metastasis ... See more keywords

Syndecan-2: Old Player in a New Field

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recommendations! Published in 2019 at "American Journal of Respiratory Cell and Molecular Biology"

DOI: 10.1165/rcmb.2019-0033ed

Abstract: Lung adenocarcinoma is a non–small-cell lung cancer and one of the most invasive forms of lung cancers associated with poor prognosis. It is characterized by distinct cellular and molecular features such as malignant epithelia comprised… read more here.

Keywords: lung; lung adenocarcinoma; cancer; sdc2 ... See more keywords

Analysis of SDC2 gene promoter methylation in whole blood for noninvasive early detection of colorectal cancer

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recommendations! Published in 2022 at "Journal of Cancer Research and Therapeutics"

DOI: 10.4103/jcrt.jcrt_1072_22

Abstract: Objectives: Considering the limitations of the current approaches to colorectal cancer (CRC) screening, scientists strived to find noninvasive and more powerful biomarkers for the early diagnosis of CRC. Nowadays, there are different sources of biomarkers… read more here.

Keywords: methylation; promoter methylation; sdc2; whole blood ... See more keywords