Syndecan 4 contributes to osteoclast differentiation induced by RANKL through enhancing autophagy.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.107275
Abstract: Periodontitis is a common chronic disease. Osteoclast differentiation contributes to alveolar bone resorption which is a distinct phenomenon during periodontitis. Syndecan 4 (SDC4), a member of the syndecan family, was found to be highly expressed… read more here.
Keywords: osteoclast differentiation; induced rankl; sdc4; differentiation induced ... See more keywords
Syndecan-4 is regulated by IL-1β in β-cells and human islets
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2020.110815
Abstract: Syndecans (SDC) are important multifunctional components of the extracellular matrix mainly described in endothelial cells. We studied the expression and regulation of SDC in cultured MIN6B1 cells and pancreatic islets. qRT-PCR revealed that syndecan-4 (SDC4)… read more here.
Keywords: human islets; sdc4; syndecan regulated; regulated cells ... See more keywords
Syndecan-4 Modulates Epithelial Gut Barrier Function and Epithelial Regeneration in Experimental Colitis.
Sign Up to like & getrecommendations! Published in 2018 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izy248
Abstract: Background The transmembrane heparan sulfate proteoglycan Syndecan-4 (Sdc4) plays an important role in the regulation of various inflammatory disorders. However, the involvement of Sdc4 in intestinal inflammation remains unknown. Therefore, we assessed the impact of… read more here.
Keywords: wound healing; sdc4; regeneration; colitis ... See more keywords
Circ_0058063 promotes progression of thyroid cancer by sponging miR-330-3p/SDC4 axis
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001307
Abstract: Circular RNA takes a crucial part in carcinogenesis. Circ_0058063 has been found to act as an oncogene in esophageal cancer and bladder cancer, but its role in thyroid cancer (TC) is still under investigation. Therefore,… read more here.
Keywords: mir 330; sdc4; cancer; circ 0058063 ... See more keywords