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   Articles with "sdcbp" as a keyword



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MicroRNA‐23a inhibits melanoma cell proliferation, migration, and invasion in mice through a negative feedback regulation of sdcbp and the MAPK/ERK signaling pathway

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recommendations! Published in 2019 at "IUBMB Life"

DOI: 10.1002/iub.1979

Abstract: Melanoma is the main cause of death associated with skin cancer. Surgical resection and adjuvant therapy are currently effective treatments, but the recurrence rate is very high. The understanding of microRNA (miR) dynamics after surgical… read more here.

Keywords: sdcbp; sdcbp mapk; signaling pathway; erk signaling ... See more keywords
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miR-216b suppresses breast cancer growth and metastasis by targeting SDCBP.

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recommendations! Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2016.10.003

Abstract: Breast cancer is the most deadly cancer among women and the second leading cause of cancer death worldwide. Treatment effectiveness is complicated with tumor invasiveness/drug resistance. To tailor treatments more effectively to individual patients, it… read more here.

Keywords: sdcbp; mir 216b; breast cancer; cancer ... See more keywords
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SDCBP promotes pancreatic cancer progression by preventing YAP1 from β-TrCP-mediated proteasomal degradation

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recommendations! Published in 2023 at "Gut"

DOI: 10.1136/gutjnl-2022-327492

Abstract: Objective Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal tumour with limited treatment options. Here, we identified syndecan binding protein (SDCBP), also known as syntenin1, as a novel targetable factor in promoting PDAC tumour progression.… read more here.

Keywords: preventing yap1; sdcbp promotes; progression; trcp mediated ... See more keywords
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Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer

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recommendations! Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.790788

Abstract: Outcomes for patients with pancreatic cancer (PC) are poor; therefore, there is an urgent need to identify novel therapeutic targets involved in the progression of PC. We previously identified 161 differentially expressed proteins (DEPs) in… read more here.

Keywords: mir 216b; pancreatic cancer; progression; expression ... See more keywords