SDCBP promotes pancreatic cancer progression by preventing YAP1 from β-TrCP-mediated proteasomal degradation
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DOI: 10.1136/gutjnl-2022-327492
Abstract: Objective Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal tumour with limited treatment options. Here, we identified syndecan binding protein (SDCBP), also known as syntenin1, as a novel targetable factor in promoting PDAC tumour progression.… read more here.
Keywords: preventing yap1; sdcbp promotes; progression; trcp mediated ... See more keywords