SA102 A COGNITIVE AND MOLECULAR ANALYSIS OF SDCCAG8, A SCHIZOPHRENIA RISK GENE THAT FUNCTIONS IN THE CENTROSOME
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.174
Abstract: Background Schizophrenia affects 1% of adults and is a major global health problem. Although aetiology is complex, genetics represents a vital tool for probing the neurobiology of the disorder in the absence of biomarkers. We… read more here.
Keywords: sdccag8; schizophrenia; molecular analysis; schizophrenia risk ... See more keywords
Characterization of two novel knock-in mouse models of syndromic retinal ciliopathy carrying hypomorphic Sdccag8 mutations
Sign Up to like & getrecommendations! Published in 2022 at "Zoological Research"
DOI: 10.24272/j.issn.2095-8137.2021.387
Abstract: Mutations in serologically defined colon cancer autoantigen protein 8 (SDCCAG8) were first identified in retinal ciliopathy families a decade ago with unknown function. To investigate the pathogenesis of SDCCAG8-associated retinal ciliopathies in vivo, we employed… read more here.
Keywords: knock; mouse; sdccag8; retinal ciliopathy ... See more keywords