SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1–Nrf2
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DOI: 10.1038/s41590-019-0482-2
Abstract: Whether screening the metabolic activity of immune cells facilitates discovery of molecular pathology remains unknown. Here we prospectively screened the extracellular acidification rate as a measure of glycolysis and the oxygen consumption rate as a… read more here.
Keywords: mitochondrial retrograde; keap1 nrf2; retrograde signaling; sdha gain ... See more keywords