Somatic SDHA mutations in paragangliomas in siblings
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DOI: 10.1097/md.0000000000022497
Abstract: Supplemental Digital Content is available in the text Abstract Rationale: Paragangliomas (PGLs) are rare neuroendocrine tumors that are strongly influenced by genetics, and succinate dehydrogenase-deficient PGLs appear to constitute one of the most important categories.… read more here.
Keywords: paragangliomas siblings; sdha mutations; mutations paragangliomas; pgl ... See more keywords
Germline SDHA mutations in children and adults with cancer
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DOI: 10.1101/mcs.a002584
Abstract: Mutations in succinate dehydrogenase complex genes predispose to familial paraganglioma-pheochromocytoma syndrome (FPG) and gastrointestinal stromal tumors (GIST). Here we describe cancer patients undergoing agnostic germline testing at Memorial Sloan Kettering Cancer Center and found to… read more here.
Keywords: germline sdha; sdha germline; sdha mutations; cancer ... See more keywords