Genomic and Metabolic Hallmarks of SDH- and FH-deficient Renal Cell Carcinomas.
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DOI: 10.1016/j.euf.2021.12.002
Abstract: BACKGROUND Succinate dehydrogenase-deficient and fumarate hydratase-deficient renal cell carcinomas (SDHRCC and FHRCC) are rare kidney cancers driven by loss of TCA cycle enzymes. OBJECTIVE To define and compare the genomic and metabolomic hallmarks of SDHRCC… read more here.
Keywords: sdh deficient; renal cell; deficient renal; sdhrcc fhrcc ... See more keywords