The oligomerization mediated by the alanine 397 residue in the transmembrane domain is crucial to sydecan-3 functions.
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DOI: 10.1016/j.cellsig.2020.109544
Abstract: Syndecans are single-pass transmembrane proteins on the cell surface that are involved in various cellular functions. Previously, we reported that both homo- and hetero-form of syndecan dimers affected their functionality. However, little is known about… read more here.
Keywords: transmembrane; alanine 397; transmembrane domain; oligomer formation ... See more keywords