Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1.
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DOI: 10.1016/j.str.2018.12.002
Abstract: SDS22 is an ancient regulator of protein phosphatase-1 (PP1). Our crystal structure of SDS22 shows that its twelve leucine-rich repeats adopt a banana-shaped fold that is shielded from solvent by capping domains at its extremities.… read more here.
Keywords: splicing factor; phosphatase pp1; sds22; structure ... See more keywords