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The Search for Potent, Smallā€Molecule HDACIs in Cancer Treatment: A Decade After Vorinostat

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Published in 2017 at "Medicinal Research Reviews"

DOI: 10.1002/med.21437

Abstract: Histone deacetylases (HDACs) play a crucial role in the remodeling of chromatin, and are involved in the epigenetic regulation of gene expression. In the last decade, inhibition of HDACs came out as a target for… read more here.

Keywords: treatment; potent small; decade; cancer ... See more keywords