Transcriptomic-Guided Drug Repositioning Supported by a New Bioinformatics Search Tool: geneXpharma
Sign Up to like & getrecommendations! Published in 2017 at "Omics A Journal of Integrative Biology"
DOI: 10.1089/omi.2017.0127
Abstract: Abstract Drug repositioning is an innovative approach to identify new therapeutic indications for existing drugs. Drug repositioning offers the promise of reducing drug development timeframes and costs, and because it involves drugs that are already… read more here.
Keywords: search tool; drug repositioning; drug; tool genexpharma ... See more keywords
VIST - a Variant-Information Search Tool for precision oncology
Sign Up to like & getrecommendations! Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-2958-3
Abstract: BackgroundDiagnosis and treatment decisions in cancer increasingly depend on a detailed analysis of the mutational status of a patient’s genome. This analysis relies on previously published information regarding the association of variations to disease progression… read more here.
Keywords: search tool; search; variant information; information search ... See more keywords
The Pharmacorank Search Tool for the Retrieval of Prioritized Protein Drug Targets and Drug Repositioning Candidates According to Selected Diseases
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DOI: 10.3390/biom12111559
Abstract: We present the Pharmacorank search tool as an objective means to obtain prioritized protein drug targets and their associated medications according to user-selected diseases. This tool could be used to obtain prioritized protein targets for… read more here.
Keywords: tool; pharmacorank search; repositioning candidates; search tool ... See more keywords
An evidence-based method for assessing the value of a search tool: a pilot study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Medical Library Association : JMLA"
DOI: 10.5195/jmla.2018.287
Abstract: Objective The objective of this study was to develop an evidence-based method with a set of metrics that could be used to assess an information search tool. Methods This pilot study analyzed a two-group convenience… read more here.
Keywords: search tool; search; group; study ... See more keywords