Microfluidic Size Exclusion Chromatography (μSEC) for Extracellular Vesicles and Plasma Protein Separation.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202104470
Abstract: Extracellular vesicles (EVs) are recognized as next generation diagnostic biomarkers due to their disease-specific biomolecular cargoes and importance in cell-cell communications. A major bottleneck in EV sample preparation is the inefficient and laborious isolation of… read more here.
Keywords: extracellular vesicles; chromatography sec; sec; size exclusion ... See more keywords
Differences between decadal decreases of boreal summer rainfall in southeastern and southwestern China in the early 2000s
Sign Up to like & getrecommendations! Published in 2018 at "Climate Dynamics"
DOI: 10.1007/s00382-018-4408-8
Abstract: On decadal time scale, the boreal summer (June–August) rainfall over southern China significantly decreased during the epoch 2003–2012 compared to that in the preceding epoch 1993–2002. This study investigates different processes involved in the decadal… read more here.
Keywords: swc; early 2000s; sec; summer ... See more keywords
Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.09.027
Abstract: The super elongation complex (SEC) is required for robust and productive transcription through release of RNA polymerase II (Pol II) with its P-TEFb module and promoting transcriptional processivity with its ELL2 subunit. Malfunction of SEC… read more here.
Keywords: cancer; processive transcription; transcription elongation; sec ... See more keywords
A Quantitative Chemoproteomic Platform to Monitor Selenocysteine Reactivity within a Complex Proteome.
Sign Up to like & getrecommendations! Published in 2018 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2018.05.017
Abstract: Mammalian selenocysteine (Sec)-containing proteins, selenoproteins, are important to (patho)physiological processes, including redox homeostasis. Sec residues have been recalcitrant to mass spectrometry-based chemoproteomic methods that enrich for reactive cysteine (Cys) residues with electrophilic chemical probes, despite… read more here.
Keywords: sec; cys; chemoproteomic platform; reactivity ... See more keywords
Kinetic resolution of sec-alcohols catalysed by Candida antarctica lipase B displaying Pichia pastoris whole-cell biocatalyst.
Sign Up to like & getrecommendations! Published in 2018 at "Enzyme and microbial technology"
DOI: 10.1016/j.enzmictec.2017.11.005
Abstract: Kinetic resolution of sec-alcohols is a green process with biocatalyst. Candida antarctica lipase B (CALB) displayed on Pichia pastoris cell-surface (Pp-CALB) was characterized in kinetic resolution of sec-alcohols with different structures. The reaction parameters including… read more here.
Keywords: resolution sec; sec; biocatalyst; kinetic resolution ... See more keywords
Association of left atrial deformation indices with left atrial appendage thrombus in patients with non valvular atrial fibrillation
Sign Up to like & getrecommendations! Published in 2020 at "Indian Heart Journal"
DOI: 10.1016/j.ihj.2020.07.010
Abstract: Aim Assessment of the value of left atrial deformation indices for prediction of left atrial appendage functioning patients with non-valvular atrial fibrillation. Method The study included 250 patients with non-valvular atrial fibrillation and normal left… read more here.
Keywords: sec; patients non; group; non valvular ... See more keywords
Transparency and fund governance efficacy: The effect of the SEC'S disclosure rule on advisory contracts
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Corporate Finance"
DOI: 10.1016/j.jcorpfin.2020.101559
Abstract: In June 2004, the SEC required mutual fund boards to disclose additional information about the inputs and processes involved in advisory contract approvals to help investors make more informed decisions and to encourage independent directors… read more here.
Keywords: sec; 2004 sec; sec amendments; advisory fees ... See more keywords
Novel method for metalloproteins determination in human breast milk by size exclusion chromatography coupled to inductively coupled plasma mass spectrometry
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.06.003
Abstract: HIGHLIGHTSNovel methodology of metalloproteins determination by SEC‐ICP‐MS in human whey milk protein fractions.Two metalloproteins have detectable concentrations of Mn, Co, Cu and Se.The levels of Mn, Co, Cu and Se were within the range reported… read more here.
Keywords: milk; sec; whey milk; metalloproteins determination ... See more keywords
Estratificación, monitorización y control del riesgo cardiovascular en pacientes con cáncer. Documento de consenso de SEC, FEC, SEOM, SEOR, SEHH, SEMG, AEEMT, AEEC y AECC
Sign Up to like & getrecommendations! Published in 2021 at "Revista Espanola De Cardiologia"
DOI: 10.1016/j.recesp.2020.11.014
Abstract: Resumen El incremento de la supervivencia del enfermo con cancer, junto con el desarrollo de nuevas terapias antitumorales, han puesto de relieve el impacto negativo que las complicaciones vasculares asociadas con el tratamiento oncohematologico tienen… read more here.
Keywords: sec; con; espanola; del ... See more keywords
Production and purification of homogenous recombinant human selenoproteins reveals a unique codon skipping event in E. coli and GPX4-specific affinity to bromosulfophthalein
Sign Up to like & getrecommendations! Published in 2021 at "Redox Biology"
DOI: 10.1016/j.redox.2021.102070
Abstract: Selenoproteins are translated via animal domain-specific elongation machineries that redefine dedicated UGA opal codons from termination of translation to selenocysteine (Sec) insertion, utilizing specific tRNA species and Sec-specific elongation factors. This has made recombinant production… read more here.
Keywords: sec contents; production; sec; gpx4 ... See more keywords
A novel weak acid activated probe for highly selective monitoring selenocysteine in living cells.
Sign Up to like & getrecommendations! Published in 2020 at "Talanta"
DOI: 10.1016/j.talanta.2020.121287
Abstract: Selenocysteine (Sec, pKa 5.8) is genetically encoded 21st amino acid into the active site of selenoproteins, which have broad functions relevant to various diseases, tissues or organs and subcellular organelles. However, many selenoproteins involved cellular… read more here.
Keywords: probe; sec; novel weak; acid activated ... See more keywords