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   Articles with "sec" as a keyword



DeepSecMS Advances DIA‐Based Selenoproteome Profiling Through Cys‐to‐Sec Proxy Training

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recommendations! Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202504109

Abstract: Selenoproteins, defined as proteins containing the 21st amino acid, selenocysteine (Sec, U), are functionally important but rare, with only 25 selenoproteins characterized in the entire human proteome to date. To comprehensively analyze selenoproteomes, previously developed… read more here.

Keywords: cys; deepsecms; proxy training; sec ... See more keywords

Molar mass determination via linear regression from SEC measurements: The case of polylactide, polycaprolactone and poly(2,2‐dimethylthrimethylene carbonate)

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recommendations! Published in 2024 at "Polymers for Advanced Technologies"

DOI: 10.1002/pat.6296

Abstract: Molar mass correction coefficients (cc) were determined for calculating the absolute molar masses of polylactide (PLA), polycaprolactone (PCL), and poly(2,2‐dimethyltrimethylene carbonate) (PDTC) in the range of 2,5–190 kg/mol, using calibration based on polystyrene standards (PS). Linear PLAs, PCLs,… read more here.

Keywords: molar mass; correction coefficients; sec; mass ... See more keywords

Microfluidic Size Exclusion Chromatography (μSEC) for Extracellular Vesicles and Plasma Protein Separation.

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recommendations! Published in 2022 at "Small"

DOI: 10.1002/smll.202104470

Abstract: Extracellular vesicles (EVs) are recognized as next generation diagnostic biomarkers due to their disease-specific biomolecular cargoes and importance in cell-cell communications. A major bottleneck in EV sample preparation is the inefficient and laborious isolation of… read more here.

Keywords: extracellular vesicles; chromatography sec; sec; size exclusion ... See more keywords

Differences between decadal decreases of boreal summer rainfall in southeastern and southwestern China in the early 2000s

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recommendations! Published in 2018 at "Climate Dynamics"

DOI: 10.1007/s00382-018-4408-8

Abstract: On decadal time scale, the boreal summer (June–August) rainfall over southern China significantly decreased during the epoch 2003–2012 compared to that in the preceding epoch 1993–2002. This study investigates different processes involved in the decadal… read more here.

Keywords: swc; early 2000s; sec; summer ... See more keywords

FDA-Approved Secukinumab Alleviates Glial Activation and Immune Cell Infiltration in MPTP-Induced Mouse Model of Parkinson’s Disease

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recommendations! Published in 2025 at "Inflammation"

DOI: 10.1007/s10753-025-02267-8

Abstract: Interleukin-17A (IL-17A) has been implicated in the progression of neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). However, the effect of the FDA-approved Secukinumab (SEC), an IL-17A inhibitor, on PD remains unclear.… read more here.

Keywords: disease; sec; activation; model ... See more keywords

Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy

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recommendations! Published in 2018 at "Cell"

DOI: 10.1016/j.cell.2018.09.027

Abstract: The super elongation complex (SEC) is required for robust and productive transcription through release of RNA polymerase II (Pol II) with its P-TEFb module and promoting transcriptional processivity with its ELL2 subunit. Malfunction of SEC… read more here.

Keywords: cancer; processive transcription; transcription elongation; sec ... See more keywords
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A Quantitative Chemoproteomic Platform to Monitor Selenocysteine Reactivity within a Complex Proteome.

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recommendations! Published in 2018 at "Cell chemical biology"

DOI: 10.1016/j.chembiol.2018.05.017

Abstract: Mammalian selenocysteine (Sec)-containing proteins, selenoproteins, are important to (patho)physiological processes, including redox homeostasis. Sec residues have been recalcitrant to mass spectrometry-based chemoproteomic methods that enrich for reactive cysteine (Cys) residues with electrophilic chemical probes, despite… read more here.

Keywords: sec; cys; chemoproteomic platform; reactivity ... See more keywords

Kinetic resolution of sec-alcohols catalysed by Candida antarctica lipase B displaying Pichia pastoris whole-cell biocatalyst.

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recommendations! Published in 2018 at "Enzyme and microbial technology"

DOI: 10.1016/j.enzmictec.2017.11.005

Abstract: Kinetic resolution of sec-alcohols is a green process with biocatalyst. Candida antarctica lipase B (CALB) displayed on Pichia pastoris cell-surface (Pp-CALB) was characterized in kinetic resolution of sec-alcohols with different structures. The reaction parameters including… read more here.

Keywords: resolution sec; sec; biocatalyst; kinetic resolution ... See more keywords
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Association of left atrial deformation indices with left atrial appendage thrombus in patients with non valvular atrial fibrillation

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recommendations! Published in 2020 at "Indian Heart Journal"

DOI: 10.1016/j.ihj.2020.07.010

Abstract: Aim Assessment of the value of left atrial deformation indices for prediction of left atrial appendage functioning patients with non-valvular atrial fibrillation. Method The study included 250 patients with non-valvular atrial fibrillation and normal left… read more here.

Keywords: sec; patients non; group; non valvular ... See more keywords
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Transparency and fund governance efficacy: The effect of the SEC'S disclosure rule on advisory contracts

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recommendations! Published in 2020 at "Journal of Corporate Finance"

DOI: 10.1016/j.jcorpfin.2020.101559

Abstract: In June 2004, the SEC required mutual fund boards to disclose additional information about the inputs and processes involved in advisory contract approvals to help investors make more informed decisions and to encourage independent directors… read more here.

Keywords: sec; 2004 sec; sec amendments; advisory fees ... See more keywords

Novel method for metalloproteins determination in human breast milk by size exclusion chromatography coupled to inductively coupled plasma mass spectrometry

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recommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"

DOI: 10.1016/j.jpba.2018.06.003

Abstract: HIGHLIGHTSNovel methodology of metalloproteins determination by SEC‐ICP‐MS in human whey milk protein fractions.Two metalloproteins have detectable concentrations of Mn, Co, Cu and Se.The levels of Mn, Co, Cu and Se were within the range reported… read more here.

Keywords: milk; sec; whey milk; metalloproteins determination ... See more keywords