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   Articles with "sec machinery" as a keyword



Physical mechanisms of the Sec machinery operation

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recommendations! Published in 2024 at "Physical Chemistry Chemical Physics"

DOI: 10.1039/d4cp03201b

Abstract: The Sec complex, composed of a motor protein SecA and a channel SecYEG, is an ATP-driven molecular machine for the transport of proteins across the plasma membrane in bacteria. Today, there is a consensus about… read more here.

Keywords: physical mechanisms; sec machinery; secyeg; mechanisms sec ... See more keywords

How Quality Control Systems AID Sec-Dependent Protein Translocation

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recommendations! Published in 2021 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2021.669376

Abstract: The evolutionarily conserved Sec machinery is responsible for transporting proteins across the cytoplasmic membrane. Protein substrates of the Sec machinery must be in an unfolded conformation in order to be translocated across (or inserted into)… read more here.

Keywords: quality control; control systems; translocation; sec machinery ... See more keywords

Selenocysteine Machinery Primarily Supports TXNRD1 and GPX4 Functions and Together They Are Functionally Linked with SCD and PRDX6

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recommendations! Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12081049

Abstract: The human genome has 25 genes coding for selenocysteine (Sec)-containing proteins, whose synthesis is supported by specialized Sec machinery proteins. Here, we carried out an analysis of the co-essentiality network to identify functional partners of… read more here.

Keywords: supports txnrd1; machinery primarily; primarily supports; machinery ... See more keywords

Rate-limiting transport of positively charged arginine residues through the Sec-machinery is integral to the mechanism of protein secretion

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recommendations! Published in 2022 at "eLife"

DOI: 10.7554/elife.77586

Abstract: Transport of proteins across and into membranes is a fundamental biological process with the vast majority being conducted by the ubiquitous Sec machinery. In bacteria, this is usually achieved when the SecY-complex engages the cytosolic… read more here.

Keywords: arginine; mechanism protein; transport; secretion ... See more keywords