It takes a sec(22b) to accrue plasma cells
Sign Up to like & getrecommendations! Published in 2023 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12629
Abstract: Antibody-secreting plasma cells (ASCs) protect from infection by secreting pathogen-specific antibodies (Abs). As Abs have a typical half-life of days to weeks, underpinning longterm humoral immunity is the requirement for longevity of ASCs and their… read more here.
Keywords: role; ascs; secretion; sec22b ... See more keywords
The endoplasmic reticulum protein SEC22B interacts with NBEAL2 and is required for megakaryocyte α-granule biogenesis.
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood.2019004276
Abstract: Studies of inherited platelet disorders have provided many insights into platelet development and function. Loss of function of neurobeachin-like 2 (NBEAL2) causes Gray Platelet Syndrome (GPS), where the absence of platelet α-granules indicates NBEAL2 is… read more here.
Keywords: biogenesis; endoplasmic reticulum; reticulum; nbeal2 required ... See more keywords