SEC24A facilitates colocalization and Ca2+ flux between the endoplasmic reticulum and mitochondria
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cell Science"
DOI: 10.1242/jcs.249276
Abstract: ABSTRACT A genome-wide screen recently identified SEC24A as a novel mediator of thapsigargin-induced cell death in HAP1 cells. Here, we determined the cellular mechanism and specificity of SEC24A-mediated cytotoxicity. Measurement of Ca2+ levels using organelle-specific… read more here.
Keywords: endoplasmic reticulum; ca2 flux; sec24a; ca2 ... See more keywords
ING5-mediated regulation of lung cancer progression via the OIP5-AS1/miR-381-3p/SEC24A axis
Sign Up to like & getrecommendations! Published in 2025 at "Translational Cancer Research"
DOI: 10.21037/tcr-2025-1284
Abstract: Background Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related deaths globally. It poses a significant threat to human health with high incidence and mortality rates. Current treatments like surgery, chemotherapy, and radiation… read more here.
Keywords: cancer; sec24a; cell; as1 mir ... See more keywords