Bioactive enmein-type 6,7-seco-ent-kaurane diterpenoids: natural products, synthetic derivatives and apoptosis related mechanism
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DOI: 10.1007/s12272-018-1078-3
Abstract: Diterpenoids are important and widely distributed natural compounds with various biological effects, including antitumor, anti-inflammatory and so on. Great efforts have been put in phytochemistry research on diterpenoids. A number of structural modified derivatives and… read more here.
Keywords: seco ent; kaurane diterpenoids; enmein type; type ... See more keywords
6,7-Seco-ent-Kauranoids Derived from Oridonin as Potential Anticancer Agents.
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DOI: 10.1021/acs.jnatprod.7b00057
Abstract: Structurally unique 6,7-seco-ent-kaurenes, which are widely distributed in the genus Isodon, have attracted considerable attention because of their antitumor activities. Previously, a convenient conversion of commercially available oridonin (1) to 6,7-seco-ent-kaurenes was developed. Herein, several… read more here.
Keywords: seco ent; anticancer agents; spiro lactone; ent ... See more keywords