Articles with "second messenger" as a keyword



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Lactate as a new second messenger shaping intracellular Mg2+ dynamics and bioenergetics.

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Published in 2020 at "Cell calcium"

DOI: 10.1016/j.ceca.2020.102329

Abstract: Mg2+ is an essential cation controlling many biochemical reactions. Recently, Daw et al. [1] have shown that l-lactate acts as a second messenger triggering a dynamic exchange of Mg2+ between the endoplasmic reticulum and mitochondria… read more here.

Keywords: mg2; messenger shaping; lactate new; new second ... See more keywords

The second messenger c-di-AMP controls natural competence via ComFB signaling protein

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Published in 2025 at "Cell Discovery"

DOI: 10.1038/s41421-025-00816-x

Abstract: Natural competence requires a contractile pilus system. Here, we provide evidence that the pilus biogenesis and natural competence in cyanobacteria are regulated by the second messenger c-di-AMP. Furthermore, we show that the ComFB signaling protein… read more here.

Keywords: natural competence; messenger amp; competence; signaling protein ... See more keywords

MASTER-NAADP: a membrane permeable precursor of the Ca2+ mobilizing second messenger NAADP

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Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-52024-y

Abstract: Upon stimulation of membrane receptors, nicotinic acid adenine dinucleotide phosphate (NAADP) is formed as second messenger within seconds and evokes Ca2+ signaling in many different cell types. Here, to directly stimulate NAADP signaling, MASTER-NAADP, a… read more here.

Keywords: naadp; master naadp; ca2; membrane ... See more keywords
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Cyclic di-AMP, a second messenger of primary importance: tertiary structures and binding mechanisms.

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Published in 2020 at "Nucleic acids research"

DOI: 10.1093/nar/gkaa112

Abstract: Cyclic diadenylate (c-di-AMP) is a widespread second messenger in bacteria and archaea that is involved in the maintenance of osmotic pressure, response to DNA damage, and control of central metabolism, biofilm formation, acid stress resistance,… read more here.

Keywords: primary importance; tertiary structures; second messenger; cyclic amp ... See more keywords

The KupA and KupB Proteins of Lactococcus lactis IL1403 Are Novel c-di-AMP Receptor Proteins Responsible for Potassium Uptake

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Published in 2019 at "Journal of Bacteriology"

DOI: 10.1128/jb.00028-19

Abstract: Potassium is an essential ion in every living cell. Even though potassium is the most abundant cation in cells, its accumulation can be toxic. Therefore, the level of potassium has to be tightly controlled. In… read more here.

Keywords: second messenger; potassium; potassium transporters; lactococcus lactis ... See more keywords

Surface-Induced cAMP Signaling Requires Multiple Features of the Pseudomonas aeruginosa Type IV Pili

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Published in 2022 at "Journal of Bacteriology"

DOI: 10.1128/jb.00186-22

Abstract: Surface sensing by P. aeruginosa requires TFP. TFP plays a critical role in the induction of the second messenger cAMP upon surface contact; this second messenger is part of a larger cascade involved in the… read more here.

Keywords: camp; surface; second messenger; tfp ... See more keywords

Making and Breaking of an Essential Poison: the Cyclases and Phosphodiesterases That Produce and Degrade the Essential Second Messenger Cyclic di-AMP in Bacteria

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Published in 2019 at "Journal of Bacteriology"

DOI: 10.1128/jb.00462-18

Abstract: Cyclic di-AMP is a second-messenger nucleotide that is produced by many bacteria and some archaea. Recent work has shown that c-di-AMP is unique among the signaling nucleotides, as this molecule is in many bacteria both… read more here.

Keywords: cyclases phosphodiesterases; second messenger; cyclic amp; many bacteria ... See more keywords

The cyclic di-GMP receptor YcgR links the second messenger with the putrescine quorum sensing system in modulation of Dickeya oryzae motility

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Published in 2025 at "mBio"

DOI: 10.1128/mbio.01016-25

Abstract: ABSTRACT Dickeya oryzae is a prevalent pathogen capable of infecting a variety of crops and plants, and its cell motility plays a key role in invasion of host and subsequent systemic infection. We recently demonstrated… read more here.

Keywords: system; motility; gmp; putrescine ... See more keywords

The Multiple Regulatory Relationship Between RNA-Chaperone Hfq and the Second Messenger c-di-GMP

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Published in 2021 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2021.689619

Abstract: RNA chaperone protein Hfq is an important post-transcriptional regulator in bacteria, while c-di-GMP is a second messenger signaling molecule widely distributed in bacteria. Both factors have been found to play key roles in post-transcriptional regulation… read more here.

Keywords: rna chaperone; gmp; regulatory relationship; second messenger ... See more keywords