Cyclization of secondarily structured oligonucleotides to single-stranded rings by using Taq DNA ligase at high temperatures
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DOI: 10.1039/c8ra02804d
Abstract: Single-stranded DNA rings play important roles in nanoarchitectures, molecular machines, DNA detection, etc. Although T4 DNA ligase has been widely employed to cyclize single-stranded oligonucleotides into rings, the cyclization efficiency is very low when the… read more here.
Keywords: single stranded; dna; taq dna; secondarily structured ... See more keywords