An Engineered Cholesterol Oxidase Catalyses Enantioselective Oxidation of Non‐steroidal Secondary Alcohols
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200075
Abstract: The enantioselective oxidation of 2° alcohols to ketones is an important reaction in synthetic chemistry, especially if it can be achieved using O2‐driven alcohol oxidases under mild reaction conditions. However to date, oxidation of secondary… read more here.
Keywords: enantioselective oxidation; oxidation; cholesterol oxidase; secondary alcohols ... See more keywords
CpNiBr(NHC) complexes as pre-catalysts in the chemoselective anaerobic oxidation of secondary aryl alcohols: Experimental and DFT studies
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Catalysis"
DOI: 10.1016/j.mcat.2016.12.023
Abstract: Abstract Nine Ni(II)-NHC complexes of the type [CpNiBr(NHC)], each containing either a symmetric or asymmetric alkyl/benzyl/phenylethyl imidazolium ligand, effectively catalysed the anaerobic oxidation of a series of secondary alcohols, including 1-phenylethanol to yield acetophenone. Catalytic… read more here.
Keywords: secondary alcohols; nhc complexes; anaerobic oxidation; cpnibr nhc ... See more keywords
Application of deuterated THENA for assigning the absolute configuration of chiral secondary alcohols
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.01.013
Abstract: Abstract The structure of a constrained bicyclic chiral derivatizing agent (CDA), 1,2,3,4-tetrahydro-1,4-epoxynaphthalene-1-carboxylic acid, THENA 1, was modified by replacing both exo-methylene protons with deuterium atoms. The modified CDA, THENA-d2 2, could be used to assign… read more here.
Keywords: secondary alcohols; absolute configuration; configuration chiral; chiral secondary ... See more keywords
Switchable β-alkylation of Secondary Alcohols with Primary Alcohols by a Well-Defined Cobalt Catalyst
Sign Up to like & getrecommendations! Published in 2021 at "Organometallics"
DOI: 10.1021/acs.organomet.1c00147
Abstract: β-alkylation of secondary alcohols with primary alcohols to selectively generate alcohols by a well-defined Co catalyst is presented. Remarkably, a low catalyst loading of 0.7 mol % can be employed... read more here.
Keywords: secondary alcohols; primary alcohols; alcohols well; catalyst ... See more keywords
Compartmentalized Nanoreactors for One-Pot Redox-Driven Transformations
Sign Up to like & getrecommendations! Published in 2019 at "ACS Catalysis"
DOI: 10.1021/acscatal.8b04667
Abstract: This contribution introduces poly(2-oxazoline)-based shell cross-linked micelles (SCMs) as nanoreactors to realize one-pot redox-driven deracemizations of secondary alcohols in aqueous media. TEMPO and Rh-TsDPEN moieties are spatially positioned into the hydrophilic corona and the hydrophobic… read more here.
Keywords: redox driven; secondary alcohols; one pot; pot redox ... See more keywords
Hydrogen Borrowing Catalysis with Secondary Alcohols: A New Route for the Generation of β-Branched Carbonyl Compounds.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.6b12840
Abstract: A hydrogen borrowing reaction employing secondary alcohols and Ph* (Me5C6) ketones to give β-branched carbonyl products is described (21 examples). This new C-C bond forming process requires low loadings of [Cp*IrCl2]2, relatively low temperatures, and… read more here.
Keywords: borrowing catalysis; hydrogen borrowing; alcohols new; catalysis secondary ... See more keywords
Aldehyde/ketone-catalyzed highly selective synthesis of 9-monoalkylated fluorenes by dehydrative C-alkylation with primary and secondary alcohols
Sign Up to like & getrecommendations! Published in 2017 at "Green Chemistry"
DOI: 10.1039/c6gc02518h
Abstract: By using aldehydes or ketones as the catalyst and screening CsOH out as the more effective base than KOH in many instances, an efficient 9-C-alkylation of fluorenes with alcohols was achieved to provide a green… read more here.
Keywords: monoalkylated fluorenes; aldehyde ketone; primary secondary; secondary alcohols ... See more keywords
Ni-Catalyzed dehydrogenative coupling of primary and secondary alcohols with methyl-N-heteroaromatics
Sign Up to like & getrecommendations! Published in 2018 at "Organic chemistry frontiers"
DOI: 10.1039/c8qo00764k
Abstract: Here we report the first base-metal catalyzed dehydrogenative coupling of primary (aromatic, heteroaromatic, and aliphatic) and secondary alcohols with methyl-N-heteroaromatics to form various C(sp3)-alkylated N-heteroaromatics. The reaction is enabled by Earth abundant, non-precious NiBr2 as… read more here.
Keywords: coupling primary; catalyzed dehydrogenative; methyl heteroaromatics; secondary alcohols ... See more keywords
Ruthenium(ii)-catalysed direct synthesis of ketazines using secondary alcohols.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc01383k
Abstract: Direct one-pot synthesis of ketazines from secondary alcohols and hydrazine hydrate catalyzed by a ruthenium pincer complex is reported, which proceeds through O-H bond activation of secondary alcohols via amine-amide metal-ligand cooperation in the catalyst.… read more here.
Keywords: direct synthesis; secondary alcohols; synthesis ketazines; catalysed direct ... See more keywords
Catalytic deoxygenation of bio-based 3-hydroxydecanoic acid to secondary alcohols and alkanes
Sign Up to like & getrecommendations! Published in 2020 at "Green Chemistry"
DOI: 10.1039/d0gc00691b
Abstract: This work comprises the selective deoxygenation of bio-derivable 3-hydroxydecanoic acid to either linear alkanes or secondary alcohols in aqueous phase and H2-atmosphere over supported metal catalysts. Among the screened catalysts, Ru-based systems were identified to… read more here.
Keywords: deoxygenation bio; hydroxydecanoic acid; catalytic deoxygenation; secondary alcohols ... See more keywords
Assignment of the Absolute Configuration of Secondary Alcohols by 13C NMR and its Correlation with Methyl-1-(chloromethyl)-oxopyrrolidine-2-carboxylate and Quantum-Mechanical GIAO Calculations
Sign Up to like & getrecommendations! Published in 2023 at "New Journal of Chemistry"
DOI: 10.1039/d2nj05887a
Abstract: Analysis of the effect of steric compression on the chemical shifts of carbons (13C NMR) in diastereoisomers is an accessible strategy for assigning the absolute configuration of secondary alcohols. Here... read more here.
Keywords: absolute configuration; secondary alcohols; assignment absolute; configuration secondary ... See more keywords