Mechanistic Insight into the Catalytic Promiscuity of Amine Dehydrogenases: Asymmetric Synthesis of Secondary and Primary Amines
Sign Up to like & getrecommendations! Published in 2019 at "Chembiochem"
DOI: 10.1002/cbic.201800626
Abstract: Biocatalytic asymmetric amination of ketones, by using amine dehydrogenases (AmDHs) or transaminases, is an efficient method for the synthesis of α‐chiral primary amines. A major challenge is to extend amination to the synthesis of secondary… read more here.
Keywords: primary amines; synthesis secondary; nad dependent; secondary amines ... See more keywords
C‐N Bond Formation Catalyzed by Ruthenium Nanoparticles Supported on N‐Doped Carbon via Acceptorless Dehydrogenation to Secondary Amines, Imines, Benzimidazoles and Quinoxalines
Sign Up to like & getrecommendations! Published in 2018 at "ChemCatChem"
DOI: 10.1002/cctc.201801525
Abstract: Ruthenium nanoparticles (NPs) supported on N‐doped carbon (Ru/N−C) were prepared by the pyrolysis of cis‐Ru(phen)2Cl2 loaded onto carbon powder (VULCAN XC72R) at 800 °C. Ru/N−C NPs (0.2 mol% Ru) selectively catalyzed either acceptorless dehydrogenation coupling (ADC) or… read more here.
Keywords: doped carbon; carbon; ruthenium nanoparticles; secondary amines ... See more keywords
Glycolaldehyde as a Bio‐Based C1 Building Block for Selective N‐Formylation of Secondary Amines
Sign Up to like & getrecommendations! Published in 2022 at "Chemsuschem"
DOI: 10.1002/cssc.202201264
Abstract: Abstract Biomass derived glycolaldehyde was employed as C1 building block for the N‐formylation of secondary amines using air as oxidant. The reaction is atom economic, highly selective and proceeds under catalyst free conditions. This strategy… read more here.
Keywords: building block; formylation secondary; secondary amines;
Synthesis of (E)‐Enaminoesters by a 1,6‐Addition/Fragmentation Cascade Involving Coumalic Acid Esters and Secondary Amines
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202400435
Abstract: Coumalic acid methyl ester (methyl coumalate), a biomass‐derived building block, was converted into (E)‐enaminoesters by an original uncatalyzed stereoselective 1,6‐addition/fragmentation cascade involving secondary amines. The transformation occurred under useful experimental conditions as a simple heating… read more here.
Keywords: cascade; coumalic acid; fragmentation; addition ... See more keywords
One-pot amination of cyclohexanone-to-secondary amines over carbon-supported Pd: Unraveling the reaction mechanism and kinetics
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.129236
Abstract: Abstract The liquid phase amination of the cyclohexanone (CyO) with aniline (PhNH2) was studied on a Pd/C catalyst using NaCO2H as a H-donor. Catalytic tests were performed in batch reactors by varying reactant concentrations (0,… read more here.
Keywords: mechanism; secondary amines; reaction; amination cyclohexanone ... See more keywords
Rhodium-catalyzed formation of silylcarbamates from the reaction of secondary amines with CO2 and hydrosilanes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2019.06.010
Abstract: Abstract The reaction of (4-methyl-pyridine-2-iloxy)dimethylsilane (NSiMe–H, 1) with [RhCl(coe)2]2 gives the rhodium(III) complex [Rh(Cl)(κ2-NSiMe)2] (2), which reacts with a stoichiometric amount of AgCF3CO2 to afford [Rh(κ2-CF3CO2)(κ2-NSiMe)2] (3). Complexes 2 and 3 have been fully characterized… read more here.
Keywords: amines co2; formation silylcarbamates; reaction secondary; secondary amines ... See more keywords
Study on the mild, rapid and selective difluorocarbene-mediated triclassification of iododifluoroacetophenone with secondary amines and tree model for product classification
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2020.131762
Abstract: Abstract Difluorocarbene is a very active and widely used intermediate in organic synthesis. In this work, a room temperature difluorocarbene-mediated triclassification reaction of iododifluoroacetophenone (2) and secondary amines with mild condition, short reaction time (only… read more here.
Keywords: tree model; difluorocarbene; difluorocarbene mediated; secondary amines ... See more keywords
Study on the reactivity and kinetics of primary and secondary amines during epoxy curing by NIR spectroscopy combined with multivariate analysis
Sign Up to like & getrecommendations! Published in 2020 at "Vibrational Spectroscopy"
DOI: 10.1016/j.vibspec.2019.102993
Abstract: Abstract The temperature of epoxy curing reaction and the change of amino reactivity for the amine curing agent have an effect on the three-dimensional network structure of the product, which in turn affect the performance… read more here.
Keywords: reactivity kinetics; secondary amines; epoxy curing; primary secondary ... See more keywords
A 19F-Labeled Isothiocyanate Derivatizing Agent for the Chiral Discrimination of Cyclic Secondary Amines.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.5c04345
Abstract: Due to the widespread applications of cyclic secondary amines in drug development, rapid methods for detecting and distinguishing chiral cyclic secondary amines have become increasingly important. In this study, we successfully present a derivatizing strategy… read more here.
Keywords: analysis; secondary amines; labeled isothiocyanate; cyclic secondary ... See more keywords
2:1 versus 1:1 Coupling of Alkylacetylenes with Secondary Amines: Selectivity Switching in 8-Quinolinolato Rhodium Catalysis.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c00094
Abstract: Both 2:1 and 1:1 couplings of alkylacetylenes with secondary amines were achieved using 8-quinolinolato rhodium catalysts and CsF. The 2:1/1:1 selectivity was switched by choosing the reaction solvent. In DMA, an unprecedented 2:1 coupling reaction… read more here.
Keywords: secondary amines; quinolinolato rhodium; alkylacetylenes secondary; versus coupling ... See more keywords
Copper-Catalyzed, Aerobic Synthesis of NH-Sulfonimidamides from Primary Sulfinamides and Secondary Amines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02804
Abstract: NH-Sulfonimidamides are prepared by copper-catalyzed coupling of primary sulfinamides with secondary amines. Neither a ligand nor an additive is needed, and air is the terminal oxidant. The reactions occur at room temperature, show good functional… read more here.
Keywords: primary sulfinamides; catalyzed aerobic; sulfinamides secondary; secondary amines ... See more keywords