High prevalence of osteonecrosis among the hemophagocytic lymphohistiocytosis population: Single institution 10‐year retrospective data review
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Hematology"
DOI: 10.1002/ajh.24828
Abstract: To the Editor: Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder that is characterized by overactive natural-killer and cytotoxic T cells that improperly trigger macrophages and subsequently leads to hemophagocytosis in bone marrow, spleen, liver, and… read more here.
Keywords: osteonecrosis; secondary hlh; diagnosis; prevalence ... See more keywords
EP18 Use of anakinra for haemophagocytic lymphohistiocytosis in adults
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DOI: 10.1093/rheumatology/keaa109.017
Abstract: Haemophagocytic lymphohistiocytosis (HLH) is a rare, life threatening syndrome characterised by severe immune activation. The primary form occurs in early childhood and is fatal without treatment. Secondary HLH can occur at any age, usually in… read more here.
Keywords: secondary hlh; treatment; haemophagocytic lymphohistiocytosis; none ... See more keywords
Functional and genetic testing in adults with HLH reveals an inflammatory profile rather than a cytotoxicity defect
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DOI: 10.1182/blood.2019003664
Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory condition. Primary HLH occurs early in life as a result of monogenic biallelic mutations affecting lymphocyte cytotoxicity. Secondary HLH occurs mostly in adults secondary to infection, lymphoma, or… read more here.
Keywords: cell cytotoxicity; cytotoxicity; secondary hlh; lymphocyte cytotoxicity ... See more keywords
Secondary hemophagocytic lymphohistiocytosis (HLH): Five years’ experience at the UTHealth McGovern Medical School at Houston, Texas.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.e19578
Abstract: e19578 Background: Secondary HLH in adults is associated to infections, malignancies, and autoimmune disorders. HLH in children has been the basis for the management and treatment of HLH in adults. Despite their clinical similarities there… read more here.
Keywords: lymphohistiocytosis hlh; hemophagocytic lymphohistiocytosis; secondary hemophagocytic; secondary hlh ... See more keywords