The focus of spatial attention during the induction of central sensitization can modulate the subsequent development of secondary hyperalgesia
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DOI: 10.1016/j.cortex.2019.11.014
Abstract: Intense or sustained activation of peripheral nociceptors can induce central sensitization. This enhanced responsiveness to nociceptive input of the central nervous system primarily manifests as an increased sensitivity to painful mechanical pinprick stimuli extending beyond… read more here.
Keywords: spatial attention; secondary hyperalgesia; central sensitization; hyperalgesia ... See more keywords
Attenuation of capsaicin-induced ongoing pain and secondary hyperalgesia during exposure to an immersive virtual reality environment
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DOI: 10.1097/pr9.0000000000000790
Abstract: Abstract Introduction: There is growing evidence that virtual reality (VR) can be used in the treatment of chronic pain conditions. However, further research is required to better understand the analgesic mechanisms during sensitised pain states.… read more here.
Keywords: pain secondary; pain; secondary hyperalgesia; ongoing pain ... See more keywords
Strength, extent and duration of secondary hyperalgesia induced by high-frequency electrical stimulation of the foot compared to the volar forearm of healthy human volunteers
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DOI: 10.1371/journal.pone.0318934
Abstract: High-frequency electrical stimulation (HFS) of the skin using a multi-pin electrode activating epidermal nociceptors is used to explore spinal central sensitization in humans. Most previous studies applied HFS to the volar forearm. To prepare for… read more here.
Keywords: secondary hyperalgesia; forearm; hyperalgesia; stimulation ... See more keywords
The influence of a manipulation of threat on experimentally-induced secondary hyperalgesia
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DOI: 10.7717/peerj.13512
Abstract: Pain is thought to be influenced by the threat value of the particular context in which it occurs. However, the mechanisms by which a threat achieves this influence on pain are unclear. Here, we explore… read more here.
Keywords: induced secondary; secondary hyperalgesia; experimentally induced; threat ... See more keywords