Secondary malignancies and survival of FCR‐treated patients with chronic lymphocytic leukemia in Central Europe
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5033
Abstract: This is the first large‐scale cross‐country analysis of patients with chronic lymphocytic leukemia (CLL) aimed to evaluate the incidence, types, and key prognostic factors of secondary malignancies, and to assess the impact on overall survival… read more here.
Keywords: patients chronic; lymphocytic leukemia; secondary malignancies; treated patients ... See more keywords
Total body irradiation as part of conditioning regimens in childhood leukemia—long-term outcome, toxicity, and secondary malignancies
Sign Up to like & getrecommendations! Published in 2021 at "Strahlentherapie und Onkologie"
DOI: 10.1007/s00066-021-01810-4
Abstract: Total body irradiation (TBI) is an established part of conditioning regimens prior to stem cell transplantation in childhood leukemia but is associated with long-term toxicity. We retrospectively analyzed survival, long-term toxicity, and secondary malignancies in… read more here.
Keywords: term; secondary malignancies; total body; long term ... See more keywords
Efficacy and safety of CT-guided high-dose-rate interstitial brachytherapy in primary and secondary malignancies of the pancreas.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of radiology"
DOI: 10.1016/j.ejrad.2018.12.020
Abstract: PURPOSE To evaluate efficacy and safety of CT-guided iBT in patients with primary and secondary malignancies of the pancreas. MATERIAL AND METHODS 13 patients with 13 lesions of the pancreatic corpus and tail were included:… read more here.
Keywords: efficacy safety; safety guided; primary secondary; malignancies pancreas ... See more keywords
CAR T-cell-associated secondary malignancies challenge current pharmacovigilance concepts
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DOI: 10.1038/s44321-024-00183-2
Abstract: Suspected adverse reactions following chimeric antigen receptor T-cell (CAR T) treatment include more and more cases of secondary T-cell malignancies. The causality assessment of such suspected reactions challenges established evaluation practices due to (i) patient… read more here.
Keywords: assessment; car; cell; case ... See more keywords
In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors.
Sign Up to like & getrecommendations! Published in 2018 at "Genome research"
DOI: 10.1101/gr.230219.117
Abstract: Cisplatin reacts with DNA and thereby likely generates a characteristic pattern of somatic mutations, called a mutational signature. Despite widespread use of cisplatin in cancer treatment and its role in contributing to secondary malignancies, its… read more here.
Keywords: secondary malignancies; cisplatin; hepatocellular carcinomas; cisplatin mutational ... See more keywords
Secondary malignancies after chronic myeloid leukaemia upon TKI treatment: Population trends and outcomes
Sign Up to like & getrecommendations! Published in 2025 at "British Journal of Haematology"
DOI: 10.1111/bjh.20226
Abstract: The life expectancy of most chronic myeloid leukaemia (CML) patients is nearly comparable to that of the general population owing to the application of tyrosine kinase inhibitors (TKIs). Hence, focus has shifted towards long‐term adverse… read more here.
Keywords: myeloid leukaemia; chronic myeloid; population; secondary malignancies ... See more keywords
Secondary Malignancies After Autologous Stem Cell Transplantations in Patients With Malignant Lymphoma and Multiple Myeloma
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Haematology"
DOI: 10.1111/ejh.14355
Abstract: Secondary malignancies are potential complications after high‐dose therapy and autologous stem cell transplantation (ASCT). Information on the detailed course of such events is scarce, yet may be essential to minimize the impact of these sequelae. read more here.
Keywords: stem cell; autologous stem; secondary malignancies; malignancies autologous ... See more keywords
Secondary Malignancies in the Era of High-Precision Radiation Therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Critical reviews in oncogenesis"
DOI: 10.1615/critrevoncog.2018025830
Abstract: Although modern radiation therapy delivers a localized distribution of ionizing energy that can be used to cure primary cancers for many patients, the inevitable radiation exposure to non-targeted normal tissue leads to a risk of… read more here.
Keywords: radiation therapy; secondary malignancies; malignancies era; era high ... See more keywords