The metabolomics reveals intraspecies variability of bioactive compounds in elicited suspension cell cultures of three Bryophyllum species
Sign Up to like & getrecommendations! Published in 2021 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2021.113322
Abstract: Abstract In this work, the combination of elicited plant suspension cultured cells (PSCCs) with untargeted metabolomics establishes a powerful, cutting-edge strategy to unravel the effects of elicitors on the biosynthetic potential of medicinal plants, as… read more here.
Keywords: bryophyllum; metabolism; secondary metabolism; suspension ... See more keywords
Unlocking a new target for streptomycetes strain improvement
Sign Up to like & getrecommendations! Published in 2020 at "Synthetic and Systems Biotechnology"
DOI: 10.1016/j.synbio.2020.02.001
Abstract: Bacteria of the Streptomyces genus are well-known producers of secondary metabolites of high medical value. They contributed nearly 60% of current antibiotics (i.e., vancomycin, daptomycin and tetracycline), as well as antifungals, antiparasitics (avermectins), anticancer drugs… read more here.
Keywords: production; metabolism; secondary metabolism; acetyl coa ... See more keywords
Fungal secondary metabolism: regulation, function and drug discovery
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DOI: 10.1038/s41579-018-0121-1
Abstract: One of the exciting movements in microbial sciences has been a refocusing and revitalization of efforts to mine the fungal secondary metabolome. The magnitude of biosynthetic gene clusters (BGCs) in a single filamentous fungal genome… read more here.
Keywords: metabolism regulation; secondary metabolism; regulation function; fungal secondary ... See more keywords
Identification of butenolide regulatory system controlling secondary metabolism in Streptomyces albus J1074
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DOI: 10.1038/s41598-017-10316-y
Abstract: A large majority of genome-encrypted chemical diversity in actinobacteria remains to be discovered, which is related to the low level of secondary metabolism genes expression. Here, we report the application of a reporter-guided screening strategy… read more here.
Keywords: albus j1074; system; streptomyces albus; metabolism ... See more keywords
Impact of root-associated strains of three Paraburkholderia species on primary and secondary metabolism of Brassica oleracea
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DOI: 10.1038/s41598-021-82238-9
Abstract: Several root-colonizing bacterial species can simultaneously promote plant growth and induce systemic resistance. How these rhizobacteria modulate plant metabolism to accommodate the carbon and energy demand from these two competing processes is largely unknown. Here,… read more here.
Keywords: metabolism; strains three; secondary metabolism; three paraburkholderia ... See more keywords
Microbiome composition modulates secondary metabolism in a multispecies bacterial community
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2212930119
Abstract: Significance Microbial communities have been implicated in human and plant disease and are essential to global biogeochemical cycles. However, our ability to reliably alter these communities is limited by insufficient understanding of the networks that… read more here.
Keywords: community; microbiome composition; secondary metabolism; composition modulates ... See more keywords
Secondary metabolism in Penicillium expansum: Emphasis on recent advances in patulin research
Sign Up to like & getrecommendations! Published in 2018 at "Critical Reviews in Food Science and Nutrition"
DOI: 10.1080/10408398.2017.1305945
Abstract: ABSTRACT The plant pathogenic fungus Penicillium expansum is a major concern of the global food industry due to its wide occurrence and ability to produce various mycotoxins, of which the most significant is patulin. Relatively… read more here.
Keywords: expansum; research; penicillium expansum; secondary metabolism ... See more keywords
Sclerotinia sclerotiorum infection triggers changes in primary and secondary metabolism in Arabidopsis thaliana.
Sign Up to like & getrecommendations! Published in 2020 at "Phytopathology"
DOI: 10.1094/phyto-04-20-0146-r
Abstract: Sclerotinia sclerotiorum is a devastating plant pathogen that causes substantial losses in various agricultural crops. Although plants have developed some well-known defense mechanisms against invasive fungi, much remains to be learned about plant responses to… read more here.
Keywords: secondary metabolism; infection; primary secondary; sclerotiorum infection ... See more keywords
Engineering Plant Secondary Metabolism in Microbial Systems1[OPEN]
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DOI: 10.1104/pp.18.01291
Abstract: An overview of common challenges and strategies underlying efforts to reconstruct plant isoprenoid, alkaloid, phenylpropanoid, and polyketide biosynthetic pathways in microbial systems. read more here.
Keywords: plant; microbial systems1; plant secondary; secondary metabolism ... See more keywords
Membrane fluidity is involved in the regulation of heat stress induced secondary metabolism in Ganoderma lucidum
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DOI: 10.1111/1462-2920.13693
Abstract: Ganoderma lucidum has become a potential model system for evaluating how environmental factors regulate the secondary metabolism of basidiomycetes. Heat stress (HS) is one of the most important environmental factors. It was previously reported that… read more here.
Keywords: secondary metabolism; membrane fluidity; membrane; heat stress ... See more keywords
Zinc-Responsive Regulator Zur Regulates Zinc Homeostasis, Secondary Metabolism, and Morphological Differentiation in Streptomyces avermitilis
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DOI: 10.1128/aem.00278-22
Abstract: Biosynthesis of secondary metabolites and morphological differentiation in bacteria are affected by environmental signals. The molecular mechanisms whereby zinc availability affects secondary metabolism and morphological differentiation remain poorly understood. ABSTRACT Zinc is an essential cofactor… read more here.
Keywords: zinc; metabolism morphological; secondary metabolism; morphological differentiation ... See more keywords