Secondary Packages cannot Protect Liquid Biopharmaceutical Formulations from Dropping-Induced Degradation.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical research"
DOI: 10.1007/s11095-021-03073-1
Abstract: PURPOSES Liquid protein-based biopharmaceutical formulations have been reported to form aggregation and protein sub-visible particles (SbVPs) during dropping (Randolph et al., J Pharm Sci 2015, 104, 602). However, effects of secondary package on liquid biopharmaceutical… read more here.
Keywords: liquid biopharmaceutical; biopharmaceutical formulations; formulation; stability ... See more keywords
Effects of Secondary Package on Freeze-Dried Biopharmaceutical Formulation Stability during Dropping.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2021.04.019
Abstract: Previously our laboratory first reported that dropping of freeze-dried monoclonal antibody (mAb) formulations could cause protein degradation and aggregation (J Pharm Sci, 2021, 1625). In this manuscript, we evaluated effects of secondary package on stability… read more here.
Keywords: dried biopharmaceutical; freeze dried; stability; secondary package ... See more keywords