Rab21, a Novel PS1 Interactor, Regulates γ-Secretase Activity via PS1 Subcellular Distribution
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DOI: 10.1007/s12035-017-0606-3
Abstract: Abstractγ-Secretase has been a therapeutical target for its key role in cleaving APP to generate β-amyloid (Aβ), the primary constituents of senile plaques and a hallmark of Alzheimer’s disease (AD) pathology. Recently, γ-secretase-associating proteins showed… read more here.
Keywords: ps1; secretase associating; secretase activity; rab21 ... See more keywords