Articles with "secrete chaperone" as a keyword



Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection

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Published in 2024 at "Science Advances"

DOI: 10.1126/sciadv.adk9884

Abstract: Molecular chaperones are protective in neurodegenerative diseases by preventing protein misfolding and aggregation, such as extracellular amyloid plaques and intracellular tau neurofibrillary tangles in Alzheimer’s disease (AD). In addition, AD is characterized by an increase… read more here.

Keywords: hspb1; secrete chaperone; astrocytes secrete; reactive astrocytes ... See more keywords