An account of in silico identification tools of secreted effector proteins in bacteria and future challenges
Sign Up to like & getrecommendations! Published in 2019 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbx078
Abstract: Abstract Bacterial pathogens secrete numerous effector proteins via six secretion systems, type I to type VI secretion systems, to adapt to new environments or to promote virulence by bacteriumâhost interactions. Many computational approaches have been… read more here.
Keywords: proteins bacteria; silico identification; effector proteins; effector ... See more keywords
The Chlamydia trachomatis secreted effector TmeA hijacks the N-WASP-ARP2/3 actin remodeling axis to facilitate cellular invasion
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1008878
Abstract: As an obligate intracellular pathogen, host cell invasion is paramount to Chlamydia trachomatis proliferation. While the mechanistic underpinnings of this essential process remain ill-defined, it is predicted to involve delivery of prepackaged effector proteins into… read more here.
Keywords: invasion; host cell; secreted effector; chlamydia trachomatis ... See more keywords