T4SEfinder: a bioinformatics tool for genome-scale prediction of bacterial type IV secreted effectors using pre-trained protein language model.
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbab420
Abstract: Bacterial type IV secretion systems (T4SSs) are versatile and membrane-spanning apparatuses, which mediate both genetic exchange and delivery of effector proteins to target eukaryotic cells. The secreted effectors (T4SEs) can affect gene expression and signal… read more here.
Keywords: bacterial type; t4sefinder; secreted effectors; pre trained ... See more keywords
Type III secreted effectors that target mitochondria
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DOI: 10.1111/cmi.13352
Abstract: A type III secretion system (T3SS) is used by Gram‐negative bacterial pathogens to secrete and translocate a battery of proteins, termed effectors, from the bacteria directly into the host cells. These effectors, which are thought… read more here.
Keywords: iii; iii secreted; secreted effectors; cell ... See more keywords
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice
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DOI: 10.1128/iai.00505-22
Abstract: The NleGs are the largest family of type 3 secreted effectors in attaching and effacing (A/E) pathogens, such as enterohemorrhagic Escherichia coli (EHEC), enteropathogenic E. coli, and Citrobacter rodentium. NleG effectors contain a conserved C-terminal… read more here.
Keywords: infection; domain; type secreted; citrobacter rodentium ... See more keywords
iT3SE-PX: Identification of Bacterial Type III Secreted Effectors Using PSSM Profiles and XGBoost Feature Selection
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2021/6690299
Abstract: Identification of bacterial type III secreted effectors (T3SEs) has become a popular research topic in the field of bioinformatics due to its crucial role in understanding host-pathogen interaction and developing better therapeutic targets against the… read more here.
Keywords: bacterial type; iii secreted; identification bacterial; secreted effectors ... See more keywords