Interference of miR-943-3p with secreted frizzled-related proteins4 (SFRP4) in an asthma mouse model
Sign Up to like & getrecommendations! Published in 2019 at "Cell and Tissue Research"
DOI: 10.1007/s00441-019-03026-6
Abstract: The aim of this study is to investigate the potential roles of miR-943-3p and its target gene secreted frizzled-related proteins4 (SFRP4) in allergic asthma and elucidate its underlying mechanism, which may prompt a new clue… read more here.
Keywords: frizzled related; mir 943; sfrp4; asthma ... See more keywords
Association of Secreted Frizzled Related Protein 4 with Type 2 Diabetes Mellitus and its complications: A South Indian hospital based case control study
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Epidemiology and Global Health"
DOI: 10.1016/j.cegh.2020.08.009
Abstract: Abstract Introduction Secreted frizzled related protein 4 (SFRP4) is a modulator of the Wnt pathway. Its secretion is regulated by interleukin-1β. Objectives Primary objective was to assess the serum levels of SFRP4 in cases of… read more here.
Keywords: control study; frizzled related; related protein; case control ... See more keywords
Secreted frizzled-related protein 4 exerts anti-atherosclerotic effects by reducing inflammation and oxidative stress.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2022.174901
Abstract: Atherosclerosis and its sequelae, such as coronary artery disease (CAD), are the most common diseases worldwide and the leading causes of morbidity and mortality in most countries. Our previous studies have shown that circulating secreted… read more here.
Keywords: related protein; sfrp4; reducing inflammation; frizzled related ... See more keywords
Secreted Frizzled-Related Protein 2 and Inflammation-Induced Skeletal Muscle Atrophy
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DOI: 10.1097/ccm.0000000000002056
Abstract: Objective: In sepsis, the disease course of critically ill patients is often complicated by muscle failure leading to ICU-acquired weakness. The myokine transforming growth factor-&bgr;1 increases during inflammation and mediates muscle atrophy in vivo. We… read more here.
Keywords: protein; frizzled related; muscle; inflammation ... See more keywords
miR-191 Inhibition Induces Apoptosis Through Reactivating Secreted Frizzled-Related Protein-1 in Cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000493654
Abstract: Background/Aims: Cholangiocarcinoma (CCA) is one of the most common malignant tumors of the biliary tract originating from biliary epithelial cells. Although many therapeutic strategies have been developed to treat CCA, the survival rate for CCA… read more here.
Keywords: frizzled related; rbe cells; cca; related protein ... See more keywords
Editorial: A Novel Monoclonal Antibody-Targeting Angiogenesis by Inhibiting Secreted Frizzled-Related Protein 2
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-019-07801-1
Abstract: The legendary surgeon-scientist Judah Folkman contributed a wealth of discoveries on the fundamental role of angiogenesis in cancer and other diseases. This line of investigation led to more than 50 angiogenesis inhibitors being investigated in… read more here.
Keywords: protein; secreted frizzled; growth; angiogenesis ... See more keywords
Hypermethylation of secreted frizzled-related proteins predicts poor prognosis in non-M3 acute myeloid leukemia
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DOI: 10.2147/ott.s136502
Abstract: Objective Secreted frizzled-related proteins (SFRPs) as Wnt signaling antagonists have been found to be dysregulated by promoter hypermethylation in several cancers including acute myeloid leukemia (AML). This study aimed to investigate the methylated status of… read more here.
Keywords: methylation; frizzled related; related proteins; hypermethylation ... See more keywords
Deregulation of Secreted Frizzled-Related Protein 5 in Nonalcoholic Fatty Liver Disease Associated with Obesity
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DOI: 10.3390/ijms22136895
Abstract: Secreted frizzled-related protein 5 (SFRP5), an antagonist of the noncanonical WNT pathway, has a controversial role in liver disease. The aim of this study was to analyze the role of SFRP5 and the noncanonical WNT… read more here.
Keywords: sfrp5; frizzled related; related protein; liver disease ... See more keywords
Increased Secreted Frizzled-Related Protein 5 mRNA Expression in the Adipose Tissue of Women with Nonalcoholic Fatty Liver Disease Associated with Obesity
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DOI: 10.3390/ijms23179871
Abstract: Secreted frizzled-related protein 5 (SFRP5) is an anti-inflammatory adipocytokine secreted by adipocytes that seems to be linked with nonalcoholic fatty liver disease (NAFLD). We aimed to evaluate the role of the SFRP5-wingless-MMTV integration site family… read more here.
Keywords: sfrp5; secreted frizzled; expression; mrna expression ... See more keywords