TGFBI secreted by mesenchymal stromal cells ameliorates osteoarthritis and is detected in extracellular vesicles.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119544
Abstract: Mesenchymal stem/stromal cells (MSCs) are of interest in the context of osteoarthritis (OA) therapy. We previously demonstrated that TGFβ-induced gene product-h3 (TGFBI/BIGH3) is downregulated in human MSCs (hMSCs) from patients with OA, suggesting a possible… read more here.
Keywords: extracellular vesicles; secreted mesenchymal; mesenchymal stromal; cells ameliorates ... See more keywords
Exosomes secreted from mesenchymal NSCLC cells to promote invasiveness and metastatic capability of recipient cells through UCHL1.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e24008
Abstract: e24008Background: Cancer-derived exosomes are intracellular signaling organelles that can act to help cancer cells invade neighboring tissues, induce epithelial-mesenchymal transition (EMT) in targ... read more here.
Keywords: secreted mesenchymal; promote invasiveness; cells promote; nsclc cells ... See more keywords