Activity of acute pancreatitis is modified by secreted protein acidic and rich in cysteine ablation
Sign Up to like & getrecommendations! Published in 2022 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12262
Abstract: Abstract Background Acute pancreatitis (AP) is a frequent cause for hospitalization. However, molecular determinants that modulate severity of experimental pancreatitis are only partially understood. Objective To investigate the role of secreted protein acidic and rich… read more here.
Keywords: rich cysteine; secreted protein; protein acidic; pancreatitis ... See more keywords
A lateral oviduct secreted protein plays a vital role for egg movement through the female reproductive tract in the brown planthopper.
Sign Up to like & getrecommendations! Published in 2021 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2021.103555
Abstract: The oviduct serves as a delivery tube for mature eggs ovulated from ovaries to egg-laying sites. Oviduct secreted components play important roles in ovulation and fertilization in mammals, however, no oviduct secreted protein has been… read more here.
Keywords: oviduct secreted; oviduct; role egg; lateral oviduct ... See more keywords
Secreted protein acidic and rich in cysteine (SPARC) regulates thermogenesis in white and brown adipocytes
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2020.110757
Abstract: SPARC, also known as osteonectin, is well known for its physiological roles in bone formation and tissue remodeling, as well as in cancer pathology; however, evidence regarding its function in adipocytes is lacking. The present… read more here.
Keywords: protein acidic; sparc; acidic rich; white brown ... See more keywords
Hypertrophic Ligamentum Flavum in Lumbar Spine Stenosis Is Associated With the Increased Expression of Secreted Protein Acidic and Rich in Cysteine.
Sign Up to like & getrecommendations! Published in 2022 at "Global spine journal"
DOI: 10.1177/21925682221138766
Abstract: STUDY DESIGN Basic research. OBJECTIVES Secreted protein acidic and rich in cysteine (SPARC) is a critical pro-fibrotic mediator. This study aims to characterize the role of SPARC in hypertrophic ligamentum flavum (LF) and fibrosis. METHODS… read more here.
Keywords: secreted protein; rich cysteine; expression; protein acidic ... See more keywords
Necator americanus Ancylostoma Secreted Protein-2 (Na-ASP-2) Binds an Ascaroside (ascr#3) in Its Fatty Acid Binding Site
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2020.608296
Abstract: During their infective stages, hookworms release excretory-secretory (E-S) products, small molecules, and proteins to help evade and suppress the host's immune system. Small molecules found in E-S products of mammalian hookworms include nematode derived metabolites… read more here.
Keywords: hookworm products; fatty acid; necator americanus; secreted protein ... See more keywords
Secreted Protein Acidic and Rich in Cysteine Mediates the Development and Progression of Diabetic Retinopathy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.869519
Abstract: Backgrounds Diabetic retinopathy (DR) is one of the most severe microvascular complications of diabetes mellitus (DM). Secreted protein acidic and rich in cysteine (SPARC) has been found to play an important role in many diseases,… read more here.
Keywords: role; secreted protein; protein acidic; diabetic retinopathy ... See more keywords
Intercellular communication involving macrophages at the maternal-fetal interface may be a pivotal mechanism of URSA: a novel discovery from transcriptomic data
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.973930
Abstract: Unexplained recurrent spontaneous abortion (URSA) is a severe challenge to reproductive females worldwide, and its etiology and pathogenesis have not yet been fully clarified. Abnormal intercellular communication between macrophages (Mφ) and decidual stromal cells (DSCs)… read more here.
Keywords: intercellular communication; communication; mechanism; secreted protein ... See more keywords
A Novel Secreted Protein-Related Gene Signature Predicts Overall Survival and Is Associated With Tumor Immunity in Patients With Lung Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.870328
Abstract: Secreted proteins are important proteins in the human proteome, accounting for approximately one-tenth of the proteome. However, the prognostic value of secreted protein-related genes has not been comprehensively explored in lung adenocarcinoma (LUAD). In this… read more here.
Keywords: secreted protein; overall survival; lung adenocarcinoma; protein related ... See more keywords
Function and Characterization of an Alanine Dehydrogenase Homolog From Nocardia seriolae
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2021.801990
Abstract: Fish nocardiosis is a chronic, systemic, granulomatous disease in aquaculture. Nocardia seriolae has been reported to be one of the main pathogenic bacteria of fish nocardiosis. There are few studies on the associated virulence factors… read more here.
Keywords: nocardia seriolae; function; secreted protein; alanine dehydrogenase ... See more keywords
Correlation between secreted protein acidic and rich in cysteine protein expression and the prognosis of postoperative patients exhibiting esophageal squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular medicine reports"
DOI: 10.3892/mmr.2017.6959
Abstract: The aim of the present study was to investigate the association between the expression level of secreted protein acidic and rich in cysteine (SPARC) and the prognosis of postoperative patients with esophageal squamous cell carcinoma… read more here.
Keywords: protein; sparc; protein acidic; prognosis ... See more keywords