Overcoming CAR-Mediated CD19 Downmodulation and Leukemia Relapse with T Lymphocytes Secreting Anti-CD19 T-cell Engagers
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DOI: 10.1158/2326-6066.cir-21-0853
Abstract: Engineered T lymphocytes secreting anti–CD19 T-cell engagers (STAb-T19) prevent the down-modulation of CD19 and result in rapid, efficient elimination of cancer cells by recruiting endogenous T cells, thus preventing CD19-positive relapses associated with CD19-targeting CAR… read more here.
Keywords: cd19 cell; cell; lymphocytes secreting; secreting anti ... See more keywords