In Vitro Generation of Human Antibody-Secreting Cells Through the Stimulation of PBMCs with Dengue Virus Particles.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1879-0_16
Abstract: The Dengue pathophysiology has had several aspects determined over the years. However, some points remain elusive, such as the metabolic factors that regulate the massive B cell differentiation into antibody-secreting cells observed in Dengue patients.… read more here.
Keywords: secreting cells; antibody secreting; dengue virus;
Th17 cells, γδ T cells and their interplay in EAE and multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2018.01.001
Abstract: Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis (MS) that shares many features with the human disease. This review will focus on the role of IL-17-secreting CD4 and γδ T cells in… read more here.
Keywords: secreting cells; th17 cells; multiple sclerosis; role ... See more keywords
Single-cell deep phenotyping of IgG-secreting cells for high-resolution immune monitoring
Sign Up to like & getrecommendations! Published in 2017 at "Nature Biotechnology"
DOI: 10.1038/nbt.3964
Abstract: Studies of the dynamics of the antibody-mediated immune response have been hampered by the absence of quantitative, high-throughput systems to analyze individual antibody-secreting cells. Here we describe a simple microfluidic system, DropMap, in which single… read more here.
Keywords: single cell; secreting cells; igg; immune monitoring ... See more keywords
Site-1 protease function is essential for the generation of antibody secreting cells and reprogramming for secretory activity
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-32705-7
Abstract: The unfolded protein response (UPR) and activation of XBP1 is necessary for high secretory efficiency and functional differentiation of antibody secreting cells (ASCs). The UPR additionally includes a branch in which membrane-bound transcription factors, exemplified… read more here.
Keywords: secreting cells; antibody secreting; secretory; site ... See more keywords
Generation of glucose sensitive insulin-secreting cells from human induced pluripotent stem cells on optimized polyethersulfone (PES) hybrid nanofibrous scaffold.
Sign Up to like & getrecommendations! Published in 2022 at "Artificial organs"
DOI: 10.1111/aor.14431
Abstract: BACKGROUND In the realm of diabetes treatment, various strategies have been tried, including islet transplantation and common drug therapies, but the limitations of these procedures and lack of responsive to the high number of patients… read more here.
Keywords: secreting cells; insulin secreting; group; stem ... See more keywords
HBV promotes the recruitment of IL‐17 secreting T cells via chemokines CCL22 and CCL17
Sign Up to like & getrecommendations! Published in 2020 at "Liver International"
DOI: 10.1111/liv.14438
Abstract: Little is known about the mechanisms of IL‐17 secreting T cells accumulation in HBV‐transfected livers. Here, we investigated the role of the chemokines CCL17, CCL20 and CCL22 in this process. read more here.
Keywords: recruitment secreting; secreting cells; hbv; hbv promotes ... See more keywords
SLC25A46 promotes mitochondrial fission and mediates resistance to lipotoxic stress in INS-1E insulin secreting cells.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cell science"
DOI: 10.1242/jcs.260049
Abstract: Glucose sensing in pancreatic beta-cells depends on oxidative phosphorylation and mitochondria-derived signals that promote insulin secretion. Using mass spectrometry-based phosphoproteomics to search for down-stream effectors of glucose dependent signal transduction in INS-1E insulinoma cells, we… read more here.
Keywords: stress; secreting cells; slc25a46; insulin secreting ... See more keywords
Diagnosis of Streptococcus pneumoniae infection using circulating antibody secreting cells
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DOI: 10.1371/journal.pone.0259644
Abstract: Background Streptococcus pneumoniae infections cause morbidity and mortality worldwide. A rapid, simple diagnostic method could reduce the time needed to introduce definitive therapy potentially improving patient outcomes. Methods We introduce two new methods for diagnosing… read more here.
Keywords: antibody secreting; pneumoniae infections; secreting cells; pneumoniae ... See more keywords
Impaired Circulating Antibody-Secreting Cells Generation Predicts the Dismal Outcome in the Elderly Septic Shock Patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s376962
Abstract: Purpose Sepsis is a condition that derives from a dysregulated host response to infection. Although B lymphocytes play a pivotal role in immune response, little is known about status of their terminally differentiated cells, antibody-secreting… read more here.
Keywords: secreting cells; elderly septic; septic shock; shock patients ... See more keywords
Anatomical basis of gastrin- and CCK-secreting cells and their functions. A review.
Sign Up to like & getrecommendations! Published in 2023 at "Biomedical research"
DOI: 10.2220/biomedres.44.81
Abstract: Gastrin and CCK (cholecystokinin), gut hormones first secreted after postprandial stages, share the C-terminal amino acids and some types of receptors to be stimulated. Both types of hormone-secreting cells are typical open-type cells which detect… read more here.
Keywords: gastrin; secreting cells; gastrin cck; basis ... See more keywords
CD11c+ B Cells Are Mainly Memory Cells, Precursors of Antibody Secreting Cells in Healthy Donors
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00032
Abstract: CD11c+ B cells have been reported to be increased in autoimmune diseases, but they are detected in the blood of healthy individuals as well. We aimed to characterize CD11c+ B cells from healthy donors by… read more here.
Keywords: secreting cells; antibody secreting; cells healthy; cd11c cells ... See more keywords