A 2019 update on TSH-secreting pituitary adenomas
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-019-01066-x
Abstract: Thyrotropin-secreting pituitary adenomas (TSH-omas) present with signs and symptoms of hyperthyroidism and they are characterized by elevated serum levels of free thyroid hormones with measurable TSH levels. TSH-omas are very infrequent, accounting for less than… read more here.
Keywords: secreting pituitary; adenomas; 2019 update; pituitary adenomas ... See more keywords
Long-term effects of somatostatin analogues in rat GH-secreting pituitary tumor cell lines
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-021-01609-1
Abstract: First-generation somatostatin analogs, octreotide (OCT) and lanreotide, are the cornerstone for the medical treatment of growth hormone (GH)-secreting pituitary tumors. A new multireceptor analog, such as pasireotide (PAS), showed better activity than OCT in long-term… read more here.
Keywords: pituitary tumor; long term; secreting pituitary; cell ... See more keywords
ACTH secreting pituitary carcinoma: Rare, durable response to concurrent chemotherapy and re-irradiation with a review of the literature. Recurrent pituitary carcinoma re-irradiation
Sign Up to like & getrecommendations! Published in 2021 at "Advances in Radiation Oncology"
DOI: 10.1016/j.adro.2021.100813
Abstract: Abstract Pituitary carcinoma (PC) is an uncommon intracranial malignancy with a high rate of metastasis, mortality, and inconsistent response to therapy. Because PC is a rare condition (0.1%-0.2% of pituitary tumors), prospective studies and observable… read more here.
Keywords: irradiation; carcinoma; response; secreting pituitary ... See more keywords
Long-Term Survival After Transformation of an Adrenocorticotropic Hormone-Secreting Pituitary Macroadenoma to a Silent Corticotroph Pituitary Carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.11.011
Abstract: BACKGROUND Pituitary carcinomas are rare and aggressive neoplasms that despite current treatment regimens continue to have a poor prognosis. Adrenocorticotrophic hormone pituitary tumors have been shown to alter their clinical manifestations with conversion to Cushing… read more here.
Keywords: hormone; silent corticotroph; hormone secreting; secreting pituitary ... See more keywords
Long-Term Effects of Intracapsular Debulking and Adjuvant Somatostatin Analogs for Growth Hormone-Secreting Pituitary Macroadenoma: 10 Years of Experience in a Single Institute.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2019.01.125
Abstract: OBJECTIVE Long-term effects of endoscopic endonasal transsphenoidal intracapsular debulking and adjuvant somatostatin analogs (SSAs) were evaluated in patients with growth hormone- (GH) secreting pituitary macroadenomas. METHODS We retrospectively reviewed the medical records of 45 patients… read more here.
Keywords: term; long term; secreting pituitary; intracapsular debulking ... See more keywords
Management of hormone-secreting pituitary adenomas
Sign Up to like & getrecommendations! Published in 2017 at "Neuro-Oncology"
DOI: 10.1093/neuonc/now130
Abstract: Pituitary adenomas are one of the most common primary central nervous system tumors and have an estimated prevalence of 17%. Approximately half of pituitary adenomas secrete distinct pituitary hormones (most often prolactin, growth hormone, or… read more here.
Keywords: hormone; hormone secreting; secreting pituitary; pituitary adenomas ... See more keywords
Contrast-enhanced 3D-T2-weighted SPACE sequence for MRI detection and localization of adrenocorticotropin (ACTH) -secreting pituitary microadenomas.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical endocrinology"
DOI: 10.1111/cen.14574
Abstract: OBJECTIVE Cushing disease is a potentially fatal endocrine disorder caused by adrenocorticotropin (ACTH) -secreting microadenomas in the pituitary gland. Accurate detection and localization of the adenomas is the key to clinical treatment. This study analyzed… read more here.
Keywords: space; space sequence; secreting pituitary; contrast enhanced ... See more keywords
Characteristics of Gut Microbiota in Patients with GH-Secreting Pituitary Adenoma
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00425-21
Abstract: Dysbiosis of gut microbiota is associated not only with intestinal disorders but also with numerous extraintestinal diseases. Growth hormone-secreting pituitary adenoma (GHPA) is an insidious disease with persistent hypersecretion of GH and IGF-1, causing increased… read more here.
Keywords: ghpa; pituitary adenoma; gut microbiota; analysis ... See more keywords
Genetic and Epigenetic Characterization of Growth Hormone–Secreting Pituitary Tumors
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Research"
DOI: 10.1158/1541-7786.mcr-19-0434
Abstract: Somatic driver mechanisms of pituitary adenoma pathogenesis have remained incompletely characterized; apart from mutations in the stimulatory Gα protein (Gαs encoded by GNAS) causing activated cAMP synthesis, pathogenic variants are rarely found in growth hormone–secreting… read more here.
Keywords: secreting pituitary; gsp; growth hormone; hormone secreting ... See more keywords
Up-regulation of sex-determining region Y-box 9 (SOX9) in growth hormone-secreting pituitary adenomas
Sign Up to like & getrecommendations! Published in 2021 at "BMC Endocrine Disorders"
DOI: 10.1186/s12902-021-00720-x
Abstract: Background Pituitary adenomas are benign brain tumors that cause considerable morbidity and neurological symptoms. SOX9 as a regulatory transcriptional mediator affects normal and tumor cell growth with an undefined role in pituitary adenomas pathogenesis. Thus,… read more here.
Keywords: secreting pituitary; pituitary adenomas; level; expression ... See more keywords
A challenging TSH/GH co-secreting pituitary adenoma with concomitant thyroid cancer; a case report and literature review
Sign Up to like & getrecommendations! Published in 2021 at "BMC Endocrine Disorders"
DOI: 10.1186/s12902-021-00839-x
Abstract: Background Thyroid stimulating hormone (TSH) secreting pituitary adenoma (TSHoma) with coexisting thyroid cancer is extremely rare, and proper treatment of both diseases may pose a unique clinical challenge. When TSHoma has plurihormonality, particularly involving the… read more here.
Keywords: tsh secreting; secreting pituitary; pituitary adenoma; cancer ... See more keywords