Cholinergic and peptidergic neurotransmission in the adrenal medulla: A dynamic control of stimulus‐secretion coupling
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DOI: 10.1002/iub.2117
Abstract: Synaptic neurotransmission at the splanchnic nerve‐chromaffin cell synapse is a chief element of the stimulus‐secretion coupling in the adrenal medullary tissue, managing and regulating the secretion of catecholamines. Making the state of play more intricate… read more here.
Keywords: stimulus secretion; splanchnic nerve; neurotransmission; secretion coupling ... See more keywords
Stimulus-Secretion Coupling in Beta-Cells: From Basic to Bedside.
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DOI: 10.1007/978-3-030-12457-1_37
Abstract: Insulin secretion in humans is usually induced by mixed meals, which upon ingestion, increase the plasma concentration of glucose, fatty acids, amino acids, and incretins like glucagon-like peptide 1. Beta-cells can stay in the off-mode,… read more here.
Keywords: beta cells; secretion; secretion coupling; calcium ... See more keywords
Novel mechanism of impaired metabolism‐secretion coupling in β‐cells: Loss of cytosolic adenosine triphosphate by leakage
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DOI: 10.1111/jdi.13094
Abstract: Zhang et al. recently proposed a new mechanism of metabolism‐secretion coupling impairment in diabetic β‐cells involving the loss of cytosolic adenosine triphosphate by leakage through plasma membrane. Hyperglycemia increases mistargeting expression of the adenosine triphosphate‐conducting… read more here.
Keywords: cytosolic adenosine; metabolism secretion; loss cytosolic; secretion coupling ... See more keywords