Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca2+ Efflux Channel in the Tubulovesicle.
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DOI: 10.1016/j.devcel.2017.04.003
Abstract: Gastric acid secretion by parietal cells requires trafficking and exocytosis of H/K-ATPase-rich tubulovesicles (TVs) toward apical membranes in response to histamine stimulation via cyclic AMP elevation. Here, we found that TRPML1 (ML1), a protein that… read more here.
Keywords: acid secretion; parietal cells; acid; gastric acid ... See more keywords