Intestinal Secretion Is a Potentially Important Clearance Mechanism for Low Metabolic Clearance Compounds.
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DOI: 10.1021/acs.jmedchem.5c00671
Abstract: Intestinal excretion/secretion (IE) from the systemic circulation via the enterocytes into the intestinal lumen has traditionally been considered a minor clearance (CL) pathway. Data from a total of 91 pharmacokinetic studies employing intravenous (IV) administration… read more here.
Keywords: potentially important; secretion potentially; clearance; secretion ... See more keywords