Bioreactor-scale cell performance and protein production can be substantially increased by using a secretion signal that drives co-translational translocation in Pichia pastoris.
Sign Up to like & getrecommendations! Published in 2020 at "New biotechnology"
DOI: 10.1016/j.nbt.2020.09.001
Abstract: Pichia pastoris (Komagataella spp.) has become one of the most important host organisms for production of heterologous proteins of biotechnological interest, many of them extracellular. The protein secretion pathway has been recognized as a limiting… read more here.
Keywords: protein; secretion signal; secretion; production ... See more keywords
Natural language processing approach to model the secretion signal of type III effectors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.1024405
Abstract: Type III effectors are proteins injected by Gram-negative bacteria into eukaryotic hosts. In many plant and animal pathogens, these effectors manipulate host cellular processes to the benefit of the bacteria. Type III effectors are secreted… read more here.
Keywords: iii effectors; secretion; type iii; secretion signal ... See more keywords