TssA: The cap protein of the Type VI secretion system tail
Sign Up to like & getrecommendations! Published in 2017 at "BioEssays"
DOI: 10.1002/bies.201600262
Abstract: The Type VI secretion system (T6SS) is a multiprotein and mosaic apparatus that delivers protein effectors into prokaryotic or eukaryotic cells. Recent data on the enteroaggregative Escherichia coli (EAEC) T6SS have provided evidence that the… read more here.
Keywords: type secretion; secretion system; tail;
Epidemiology and molecular characteristics of the type VI secretion system in Klebsiella pneumoniae isolated from bloodstream infections
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23459
Abstract: The type VI secretion system (T6SS) has been identified as a novel virulence factor. This study aimed to investigate the prevalence of the T6SS genes in Klebsiella pneumoniae‐induced bloodstream infections (BSIs). We also evaluated clinical… read more here.
Keywords: secretion system; type secretion; epidemiology; molecular characteristics ... See more keywords
The Structure of the Type III Secretion System Needle Complex.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2019_178
Abstract: The type III secretion system (T3SS) is an essential virulence factor of many pathogenic bacterial species including Salmonella, Yersinia, Shigella and enteropathogenic Escherichia coli (EPEC). It is an intricate molecular machine that spans the bacterial… read more here.
Keywords: needle complex; secretion system; system; iii secretion ... See more keywords
Structures of Type III Secretion System Needle Filaments.
Sign Up to like & getrecommendations! Published in 2020 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2019_192
Abstract: Among the Gram-negative bacterial secretion systems, type III secretion systems (T3SS) possess a unique extracellular molecular apparatus called the needle. This macromolecular protein assembly is a nanometre-size filament formed by the helical arrangement of hundreds… read more here.
Keywords: secretion; secretion system; iii secretion; structures type ... See more keywords
A Method for Characterizing the Type III Secretion System's Contribution to Pathogenesis: Homologous Recombination to Generate Yersinia pestis Type III Secretion System Mutants.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6649-3_13
Abstract: The type III (T3S) secretion system of many gram-negative bacteria is a surface-exposed protein secretion apparatus used to directly inject bacterial effector molecules into eukaryotic cells. These effector molecules contribute to bacterial pathogenesis in many… read more here.
Keywords: secretion; secretion system; system; iii secretion ... See more keywords
Identification of the Targets of Type III Secretion System Inhibitors.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6649-3_18
Abstract: A type III secretion system (T3SS) Inhibitor can be utilized for study in the research lab but also progressed into drug development. Since many pathogenic Gram-negative bacteria utilize this highly conserved system as a virulence… read more here.
Keywords: inhibitor; secretion system; system; iii secretion ... See more keywords
Isolation of the Dot/Icm Type IV Secretion System Core Complex from Legionella pneumophila.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9048-1_15
Abstract: Legionella utilizes specialized protein secretion machinery called the type IV secretion system encoded by dot/icm genes to modulate host cellular systems. We describe here the procedure to isolate the core complex of the Dot/Icm type… read more here.
Keywords: type secretion; dot icm; secretion; secretion system ... See more keywords
Recent paradigm shift in the assembly of bacterial tripartite efflux pumps and the type I secretion system
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Microbiology"
DOI: 10.1007/s12275-019-8520-1
Abstract: Tripartite efflux pumps and the type I secretion system of Gram-negative bacteria are large protein complexes that span the entire cell envelope. These complexes expel antibiotics and other toxic substances or transport protein toxins from… read more here.
Keywords: secretion system; pumps type; type secretion; efflux pumps ... See more keywords
Identification of a potent inhibitor of type II secretion system from Pseudomonas aeruginosa.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.04.055
Abstract: Pseudomonas aeruginosa is an opportunistic pathogen infecting human population. The pathogen is becoming a serious health problem due to its ability to evade normal immune response of the host and multiple drug resistance to many… read more here.
Keywords: pseudomonas aeruginosa; secretion system; secretion; system ... See more keywords
Inside the Chamber of Secrets of the Type III Secretion System
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.02.028
Abstract: The bacterial type III secretion system is a specialized machine that injects effectors into eukaryotic cells to manipulate the host cell physiology. In this issue of Cell, Hu et al. use cryo-electron tomography to reveal an… read more here.
Keywords: iii secretion; secretion system; type iii; inside chamber ... See more keywords
Salmonella SPI-2 type III secretion system-dependent inhibition of antigen presentation and T cell function.
Sign Up to like & getrecommendations! Published in 2019 at "Immunology letters"
DOI: 10.1016/j.imlet.2019.01.006
Abstract: Salmonella enterica serovars infect a broad range of mammalian hosts, including humans, causing both gastrointestinal and systemic diseases. Effective immune responses to Salmonella infections depend largely on CD4+ T cell activation by dendritic cells (DCs).… read more here.
Keywords: secretion system; iii secretion; spi type; cell ... See more keywords