Dental pulp stem cell secretome ameliorates d‐galactose induced accelerated aging in rat model
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3723
Abstract: Advancing age is associated with several diseases and disorders due to multiorgan atrophy. The increasing proportion of elderly humans demands the identification of means to counteract aging and age‐associated disorders. There is an increased depletion… read more here.
Keywords: stem cell; secretome; stem; stem cells ... See more keywords
Secretome of Undifferentiated Neural Progenitor Cells Induces Histological and Motor Improvements in a Rat Model of Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.18-0009
Abstract: Parkinson's disease (PD) is a progressive neurodegenerative movement disorder that results from the death of dopamine (DA) neurons. Over recent years, differentiated or undifferentiated neural stem cells (NSCs) transplantation has been widely used as a… read more here.
Keywords: medicine; undifferentiated neural; secretome; parkinson disease ... See more keywords
Conditioning of myoblast secretome using mesenchymal stem/stromal cell spheroids improves bone repair.
Sign Up to like & getrecommendations! Published in 2019 at "Bone"
DOI: 10.1016/j.bone.2019.05.018
Abstract: Local muscle loss associated with open fractures remains an obstacle to functional recovery and bone healing. Muscle cells secrete bioactive myokines that elicit autocrine and paracrine effects and initiate signaling pathways for regenerating damaged muscle… read more here.
Keywords: conditioned media; muscle; stem stromal; bone ... See more keywords
Progresses on bacterial secretomes enlighten research on Mycoplasma secretome.
Sign Up to like & getrecommendations! Published in 2020 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2020.104160
Abstract: Bacterial secretome is a comprehensive catalog of bacterial proteins that are released or secreted outside the cells. They offer a number of factors that possess several significant roles in virulence as well as cell to… read more here.
Keywords: mycoplasma; research; bacterial secretomes; progresses bacterial ... See more keywords
Atrial fibrillation is perpetuated by human heart secretome in ex-vivo langendorff-perfused hearts
Sign Up to like & getrecommendations! Published in 2024 at "Europace"
DOI: 10.1093/europace/euae102.005
Abstract: Abstract Introduction Atrial fibrillation (AF) confers high morbidity and mortality, yet parts of the underlying pathophysiology remain elusive. Left atrial (LA) pressure is altered by the presence of AF and vice-versa. The cardiac secretome might… read more here.
Keywords: pressure; vivo; serum; secretome ... See more keywords
Secretome from estrogen-responding human placenta-derived mesenchymal stem cells rescues ovarian function and circadian rhythm in mice with cyclophosphamide-induced primary ovarian insufficiency
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biomedical Science"
DOI: 10.1186/s12929-024-01085-8
Abstract: Primary ovarian insufficiency (POI) is an early decline in ovarian function that leads to ovarian failure. Conventional treatments for POI are inadequate, and treatments based on mesenchymal stem cells (MSCs) have emerged as an option.… read more here.
Keywords: circadian rhythm; secretome; rhythm; stem ... See more keywords
Priming mesenchymal stromal cells with neurotrophic factors boosts the neuro-regenerative potential of their secretome.
Sign Up to like & getrecommendations! Published in 2023 at "Regenerative medicine"
DOI: 10.2217/rme-2022-0201
Abstract: Aim: To explore the neuroprotective potential of the secretome (conditioned medium, CM) derived from neurotrophic factors-primed mesenchymal stromal cells (MSCs; primed CM) using an endoplasmic reticulum (ER) stress-induced in vitro model system. Methods: Establishment of… read more here.
Keywords: neurotrophic factors; stress; mesenchymal stromal; secretome ... See more keywords
The mammosphere-derived epithelial cell secretome modulates neutrophil functions in the bovine model
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1367432
Abstract: Background Innovative therapies against bacterial infections are needed. One approach is to focus on host-directed immunotherapy (HDT), with treatments that exploit natural processes of the host immune system. The goals of this type of therapy… read more here.
Keywords: derived epithelial; neutrophil functions; secretome; cell ... See more keywords
Identification and analysis of the secretome of plant pathogenic fungi reveals lifestyle adaptation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1171618
Abstract: The secretory proteome plays an important role in the pathogenesis of phytopathogenic fungi. However, the relationship between the large-scale secretome of phytopathogenic fungi and their lifestyle is not fully understood. In the present study, the… read more here.
Keywords: secretome; fungi; pathogenic fungi; lifestyle adaptation ... See more keywords
Enhanced 3T3-L1 Differentiation into Adipocytes by Pioglitazone Pharmacological Activation of Peroxisome Proliferator Activated Receptor-Gamma (PPAR-γ)
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11060806
Abstract: Simple Summary Pioglitazone is a potent activator of PPAR-γ, a transcriptional factor that is involved in insulin sensibilization and adipocyte differentiation. Here, we propose an optimized methodology for adipocyte differentiation that is critical for secretome… read more here.
Keywords: methodology; secretome; biology; pioglitazone ... See more keywords
Dental Mesenchymal Stem Cell Secretome: An Intriguing Approach for Neuroprotection and Neuroregeneration
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23010456
Abstract: Mesenchymal stem cells (MSCs) are known for their beneficial effects and regenerative potential. In particular, dental-derived MSCs have the advantage of easier accessibility and a non-invasive isolation method. Moreover, thanks to their neural crest origin,… read more here.
Keywords: stem; dental mscs; neuroregeneration; mesenchymal stem ... See more keywords